Department of General Surgery, University Hospital of Trieste, Strada di Fiume, 447, Trieste, Italy.
Obes Surg. 2012 Nov;22(11):1686-9. doi: 10.1007/s11695-012-0700-6.
Obesity is an increasing health problem worldwide. The intragastric balloon as a temporary endoscopic treatment of obesity can play an important role among the aforementioned group of obese individuals. It can also be used as a preoperative test before subjecting patients to restrictive bariatric surgery. Furthermore, the intragastric device may be applied to patients affected by severe obesity as a "bridge treatment" before they undergo major surgery in order to reduce chances of operation-related risks. To date, there are insufficient data in the literature on the long-term results of the intragastric balloon.
Our study includes an analysis of our experience with Heliosphere® BAG from 2006 through to 2010, concerning early weight loss and weight loss maintenance over at least 18 months since the device's removal. The 32 patients who completed the 6-month treatment had recorded a mean weight loss of 12.66 kg and a mean overweight loss of 24.37 % (SD, 12.74).
A total of 16 patients are subjected to an 18-month follow-up. Their pretreatment and long-term body mass index (BMI) were calculated: 6 months later, when devices were removed, they showed a mean weight of 99.75 kg (SD, 17.90; p < 0.001) and a mean weight loss of 13.62 kg and 26.14 % (SD, 12.79). 18 months after removing Heliosphere® BAG, the 16 patients' mean BMI was 37.28 kg/m² (SD, 5.41; p = 0.004), with a mean weight of 103.56 kg (SD 17.25; p = 0.0125), and a mean weight loss of 9.8 kg or 18.2 % (SD, 12.07).
Heliosphere® BAG enables modest short-term weight loss with little side effects, although mid/long-term follow-up may entail partial weight gain. We believe it can be considered a useful bridge treatment in bariatric surgery in order to reduce chances of preoperative risks.
肥胖是一个日益严重的全球健康问题。胃内球囊作为一种肥胖的临时内镜治疗方法，可以在上述肥胖人群中发挥重要作用。它也可以作为限制性减肥手术前的术前测试。此外，胃内装置可应用于因严重肥胖而接受重大手术的患者，作为主要手术前的“桥接治疗”，以降低手术相关风险的机会。迄今为止，文献中关于胃内球囊的长期结果的数据不足。
我们的研究分析了我们在 2006 年至 2010 年间使用 Heliosphere® BAG 的经验，涉及自设备移除以来至少 18 个月的早期体重减轻和体重维持。完成 6 个月治疗的 32 名患者记录的平均体重减轻为 12.66 公斤，平均超重减轻 24.37%（SD，12.74）。
共有 16 名患者接受了 18 个月的随访。计算了他们的预处理和长期体重指数（BMI）：在 6 个月后，当设备被移除时，他们的平均体重为 99.75 公斤（SD，17.90；p<0.001），平均体重减轻 13.62 公斤和 26.14%（SD，12.79）。在移除 Heliosphere® BAG 18 个月后，16 名患者的平均 BMI 为 37.28kg/m²（SD，5.41；p=0.004），平均体重为 103.56 公斤（SD 17.25；p=0.0125），平均体重减轻 9.8 公斤或 18.2%（SD，12.07）。
Heliosphere® BAG 可实现适度的短期体重减轻，副作用小，尽管中/长期随访可能会导致部分体重增加。我们认为，它可以被认为是减肥手术中的一种有用的桥接治疗方法，以降低术前风险的机会。
