Hochberg M C, Fox R, Nelson K E, Saah A
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
AIDS. 1990 Nov;4(11):1149-51.
Reiter's syndrome has been reported to occur in up to 10% of patients with HIV infection. However, no properly controlled epidemiological studies have been conducted to determine whether HIV infection is an independent risk factor or whether the immunodeficiency induced by HIV infection is permissive for infection with other arthritogenic organisms. The prevalence and incidence of Reiter's syndrome were determined in 1133 homosexual/bisexual men enrolled in the Johns Hopkins Multicenter AIDS Cohort Study. There was no difference in the prevalence of Reiter's syndrome at entry into the study in 1984 between 357 HIV-positive and 776 HIV-negative men: five per 1000 in both groups. During 5 years' follow-up, one case of Reiter's syndrome developed among each group of HIV-positive and HIV-negative men. These data fail to support a direct etiological role for HIV infection in the development of Reiter's syndrome.
据报道，赖特综合征在高达10%的HIV感染患者中出现。然而，尚未进行适当对照的流行病学研究来确定HIV感染是否为独立危险因素，或者HIV感染所致的免疫缺陷是否会导致感染其他致关节炎病原体。在参与约翰霍普金斯多中心艾滋病队列研究的1133名同性恋/双性恋男性中确定了赖特综合征的患病率和发病率。1984年研究开始时，357名HIV阳性男性和776名HIV阴性男性的赖特综合征患病率没有差异：两组均为每1000人中有5人患病。在5年的随访期间，HIV阳性组和HIV阴性组各有1例赖特综合征发生。这些数据不支持HIV感染在赖特综合征发生中起直接病因作用。
