Burkholder Tanya, Foltz Charmaine, Karlsson Eleanor, Linton C Garry, Smith Joanne M
Curr Protoc Mouse Biol. 2012 Jun;2:145-165. doi: 10.1002/9780470942390.mo110217. Epub 2012 Jun 1.
Good science and good animal care go hand in hand. A sick or distressed animal does not produce the reliable results that a healthy and unstressed animal produces. This unit describes the essentials of assessing mouse health, colony health surveillance, common conditions, and determination of appropriate endpoints. Understanding the health and well-being of the mice used in research enables the investigator to optimize research results and animal care.
优秀的科学研究与良好的动物护理相辅相成。生病或处于应激状态的动物无法产生健康且无压力的动物所能产生的可靠结果。本单元介绍了评估小鼠健康状况、群体健康监测、常见病症以及确定合适终点的要点。了解用于研究的小鼠的健康和福祉有助于研究人员优化研究结果并做好动物护理工作。