Anhui Medical University, Hefei, Anhui Province, China.
Headache. 2012 Nov-Dec;52(10):1483-98. doi: 10.1111/j.1526-4610.2012.02222.x. Epub 2012 Jul 23.
The study aimed to explore the impairment of time perception in migraineurs.
Headache is the most common pain syndrome in middle-aged adults, and migraine is highly prevalent and severely disabling. Although the mechanisms of and the therapies for migraines have long been explored, less is known about the functional impairments associated with them, especially the impairment in time perception, that is, the ability to estimate the passage of time.
In this study, we used a temporal reproduction task to assess the estimation of the duration of visual stimulus in 27 migraine patients. The stimulus was delivered at different intervals over the milliseconds and seconds range.
In the setting of an interstimulus interval for 1 second and an interstimulus interval for 5 seconds in the 600-millisecond-duration reproduction task, the migraineurs showed impairment in time perception, and in that they significantly overestimated the duration, as compared with the healthy subjects. When compared with the healthy controls for the 3-second and 5-second duration reproduction task, migraineurs in the setting of an interstimulus interval for 1 second and an interstimulus interval for 5 seconds did not show impairment in time perception.
This study indicates that not only is time perception impaired in migraineurs, but that this impairment is exhibited for durations in the milliseconds range, and not the seconds range.
本研究旨在探讨偏头痛患者时间感知的损害。
头痛是中年人群中最常见的疼痛综合征，偏头痛发病率高且致残严重。尽管偏头痛的发病机制和治疗方法早已被探索，但人们对与之相关的功能障碍知之甚少，尤其是时间感知的损害，即估计时间流逝的能力。
在这项研究中，我们使用时间复制任务来评估 27 名偏头痛患者对视觉刺激持续时间的估计。刺激在毫秒和秒的范围内以不同的时间间隔呈现。
在 600 毫秒的复制任务中，刺激间隔为 1 秒和 5 秒时，偏头痛患者表现出时间感知受损，即他们显著高估了持续时间，与健康受试者相比。与健康对照组相比，在刺激间隔为 1 秒和 5 秒的 3 秒和 5 秒的复制任务中，偏头痛患者并未表现出时间感知受损。
本研究表明，偏头痛患者不仅时间感知受损，而且这种损害在毫秒范围内表现出来，而不是在秒范围内。
