Maggiorini M, Bühler B, Walter M, Oelz O
Department of Medicine, University Hospital Zürich.
BMJ. 1990 Oct 13;301(6756):853-5. doi: 10.1136/bmj.301.6756.853.
To assess the prevalence of symptoms and signs of acute mountain sickness of the Swiss Alps.
A study using an interview and clinical examination in a representative population of mountaineers. Positive symptoms and signs were assigned scores to quantify the severity of acute mountain sickness.
Four huts in the Swiss Alps at 2850 m, 3050 m, 3650 m, and 4559 m.
466 Climbers, mostly recreational: 47 at 2850 m, 128 at 3050 m, 82 at 3650, and 209 at 4559 m.
In all, 117 of the subjects were entirely free of symptoms and clinical signs of acute mountain sickness; 191 had one or two symptoms and signs; and 158 had more than two. Those with more than two symptoms and signs were defined as suffering from acute mountain sickness. At 4559 m 11 climbers presented with high altitude pulmonary oedema or cerebral oedema, or both. Men and women were equally affected. The prevalence of acute mountain sickness correlated with altitude: it was 9% at 2850 m, 13% at 3050 m, 34% at 3650 m, and 53% at 4559 m. The most frequent symptoms and signs were insomnia, headache, peripheral oedema, and scanty pulmonary rales. Severe headache, vomiting, dizziness, tachypnoea, and pronounced pulmonary rales were associated with other symptoms and signs and therefore characteristic of acute mountain sickness.
Acute mountain sickness is not an uncommon disease at moderately high altitude--that is, above 2800 m. Severe headache, vomiting, dizziness, tachypnoea, and pronounced pulmonary rales indicate severe acute mountain sickness, and subjects who suffer these should immediately descend to lower altitudes.
评估瑞士阿尔卑斯山急性高原病症状和体征的患病率。
一项对登山者代表性人群进行访谈和临床检查的研究。对阳性症状和体征进行评分以量化急性高原病的严重程度。
瑞士阿尔卑斯山海拔2850米、3050米、3650米和4559米处的四个小屋。
466名登山者,大多为业余登山者:2850米处47人,3050米处128人,3650米处82人,4559米处209人。
总共117名受试者完全没有急性高原病的症状和临床体征;191人有一到两个症状和体征;158人有两个以上症状和体征。有两个以上症状和体征的人被定义为患有急性高原病。在4559米处,11名登山者出现高原肺水肿或脑水肿,或两者皆有。男性和女性受影响程度相同。急性高原病的患病率与海拔高度相关:2850米处为9%,3050米处为13%,3650米处为34%,4559米处为53%。最常见的症状和体征是失眠、头痛、外周水肿和肺部少量啰音。严重头痛、呕吐、头晕、呼吸急促和明显的肺部啰音与其他症状和体征相关,因此是急性高原病的特征。
急性高原病在中等高度海拔(即2800米以上)并非罕见疾病。严重头痛、呕吐、头晕、呼吸急促和明显的肺部啰音表明患有严重急性高原病,出现这些症状的受试者应立即下到较低海拔处。