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一组采用自体浓缩血浆注射联合运动及治疗性超声检查治疗慢性跟腱病的前瞻性患者。

A prospective series of patients with chronic Achilles tendinopathy treated with autologous-conditioned plasma injections combined with exercise and therapeutic ultrasonography.

作者信息

Deans Victoria M, Miller Alison, Ramos James

机构信息

Department of Trauma and Orthopaedics, Birmingham Heartlands Hospital, Birmington, United Kingdom.

出版信息

J Foot Ankle Surg. 2012 Nov-Dec;51(6):706-10. doi: 10.1053/j.jfas.2012.06.009. Epub 2012 Jul 21.

DOI:10.1053/j.jfas.2012.06.009
PMID:22824319
Abstract

Chronic Achilles tendinopathy is a difficult problem to manage, because it can result in significant patient morbidity. We conducted a prospective case series involving 26 patients (2 bilateral cases) with painful and ultrasound-confirmed Achilles tendinopathy for a minimum duration of 6 months. Our objective was to assess whether this condition can be effectively treated with a treatment protocol combining an intratendinous autologous-conditioned plasma injection followed by a standardized rehabilitation protocol. The rehabilitation protocol consisted of full weightbearing in a pneumatic cast boot for 6 weeks, therapeutic ultrasound treatment, and an eccentric exercise program. Our results showed statistically significant improvements in terms of pain (p < .0001), other symptoms (p = .0003), activities of daily living (p = .0002), sports activities (p = .0001), and quality of life (p = .0002). We believe that the use of autologous-conditioned plasma can provide a potential treatment solution for chronic Achilles tendinopathy.

摘要

慢性跟腱病是一个难以处理的问题,因为它会导致患者出现明显的发病情况。我们开展了一项前瞻性病例系列研究,纳入了26例(2例双侧病例)经超声确诊、病程至少6个月的疼痛性跟腱病患者。我们的目的是评估采用一种先进行腱内自体浓缩血浆注射,随后进行标准化康复方案的治疗方案能否有效治疗这种疾病。康复方案包括在气动石膏靴中完全负重6周、接受超声治疗以及进行离心运动计划。我们的结果显示,在疼痛(p <.0001)、其他症状(p =.0003)、日常生活活动(p =.0002)、体育活动(p =.0001)和生活质量(p =.0002)方面均有统计学上的显著改善。我们认为,使用自体浓缩血浆可为慢性跟腱病提供一种潜在的治疗方案。

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