Department of Obstetrics, Gynecology and Reproductive Biology, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Obstet Gynecol. 2012 Aug;120(2 Pt 1):284-91. doi: 10.1097/AOG.0b013e3182602c7d.
To compare surgical outcomes of laparoscopic myomectomy and robot-assisted laparoscopic myomectomy.
Retrospective cohort study of 115 consecutive laparoscopic myomectomy and 174 consecutive robot-assisted laparoscopic myomectomy performed at Brigham and Women's Hospital over a period of 31 months. Uterine incisions were closed in multiple layers (running barbed suture was used for most cases in the laparoscopic myomectomy group). Surgical outcomes measured included operative time, estimated intraoperative blood loss, length of hospital stay, and perioperative complications. Odds ratios and 95% confidence intervals were calculated from multivariable logistic regression models; adjusted geometric means were estimated from linear regression models on logged outcomes because of skewed distributions.
Surgical groups were similar in age, body mass index, and leiomyoma characteristics. Robot-assisted laparoscopic myomectomy had significantly longer operative time than laparoscopic myomectomy (adjusted geometric mean of 195.1 compared with 118.3 minutes, P<.001) and higher estimated blood loss (adjusted geometric mean of 110.0 compared with 85.9 mL, P=.04), but postoperative complications were similar.
Robot-assisted laparoscopic myomectomy and laparoscopic myomectomy have similar operative outcomes in a high-volume surgical practice. Operative time and intraoperative estimated blood loss were significantly greater in the robot-assisted laparoscopic myomectomy group, but the level of statistical significance for intraoperative estimated blood loss was marginal and the clinical significance was undetermined. Use of barbed suture in the laparoscopic myomectomy group may account for these differences.
II.
比较腹腔镜子宫肌瘤剔除术和机器人辅助腹腔镜子宫肌瘤剔除术的手术结果。
这是一项回顾性队列研究,纳入了在 31 个月期间于布莱根妇女医院连续进行的 115 例腹腔镜子宫肌瘤剔除术和 174 例机器人辅助腹腔镜子宫肌瘤剔除术。子宫切口采用多层缝合(在腹腔镜子宫肌瘤剔除术组的大多数情况下使用可吸收滑线)。测量的手术结果包括手术时间、估计术中失血量、住院时间和围手术期并发症。使用多变量逻辑回归模型计算比值比和 95%置信区间;由于分布偏态,对数结果的线性回归模型估计调整后的几何均数。
手术组在年龄、体重指数和子宫肌瘤特征方面相似。机器人辅助腹腔镜子宫肌瘤剔除术的手术时间明显长于腹腔镜子宫肌瘤剔除术(调整后的几何均数分别为 195.1 分钟和 118.3 分钟,P<.001),估计术中失血量也更高(调整后的几何均数分别为 110.0 毫升和 85.9 毫升,P=.04),但术后并发症相似。
在高容量手术实践中,机器人辅助腹腔镜子宫肌瘤剔除术和腹腔镜子宫肌瘤剔除术具有相似的手术结果。机器人辅助腹腔镜子宫肌瘤剔除术组的手术时间和术中估计失血量明显更大,但术中估计失血量的统计学显著性水平临界,临床意义不确定。腹腔镜子宫肌瘤剔除术组使用可吸收滑线可能是造成这些差异的原因。
II 级。