Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 800 East Leigh Street, Biotech One, PO Box 980126, Richmond, VA 23298-0126, USA.
Curr Psychiatry Rep. 2012 Oct;14(5):469-77. doi: 10.1007/s11920-012-0300-0.
There is a significant need for advanced understanding of treatment of co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUD). Approximately half of individuals seeking SUD treatment meet criteria for current PTSD, and individuals with co-occurring PTSD-SUD tend to have poorer treatment outcomes compared with those without such comorbidity. However, there is not sufficient empirical evidence to determine a best course of treatment for these individuals. This paper provides a review of the literature relevant to the treatment of co-occurring PTSD-SUD. To date, treatment studies have focused primarily on non-exposure-based psychosocial treatments, exposure-based psychosocial treatments, and medication trials. The most promising outcome data thus far are for psychosocial treatments that incorporate an exposure therapy component; however, further research is needed, particularly as related to how best to implement these approaches in real-world treatment settings.
对于同时患有创伤后应激障碍（PTSD）和物质使用障碍（SUD）的治疗方法，我们需要有更深入的理解。大约一半寻求 SUD 治疗的人符合当前 PTSD 的标准，而同时患有 PTSD-SUD 的人往往比没有这种合并症的人治疗效果更差。然而，目前还没有足够的经验证据来确定针对这些人的最佳治疗方案。本文综述了与 PTSD-SUD 治疗相关的文献。迄今为止，治疗研究主要集中在非暴露为基础的心理社会治疗、暴露为基础的心理社会治疗和药物试验上。到目前为止，最有希望的结果数据是对于包含暴露疗法的心理社会治疗；然而，还需要进一步的研究，特别是如何在现实治疗环境中最好地实施这些方法。
