Hildebrand Anja, Behrendt Silke, Hoyer Jürgen
a Institute of Psychology, University of Erlangen-Nuremberg , Erlangen , Germany.
Psychother Res. 2015;25(5):565-82. doi: 10.1080/10503307.2014.923125. Epub 2014 Jun 26.
We investigated the role of comorbid posttraumatic stress disorder (CO-PTSD) in substance use disorder (DSM-IV/ICD-10 substance abuse or dependence, SUD) treatment. We conducted a systematic review of treatment outcome studies in SUD patients with and without CO-PTSD from 2000 to 2011. The N = 22 studies found differed clearly with regard to methodology and the sufficiency of provided study information, limiting their comparability. Remarkably, no consistent indication of a negative effect of CO-PTSD on the reported SUD treatment outcome was found. In addition to CO-PTSD, we point out possible further effect modifiers which need to be better understood. Finally, we emphasize the requirements for future research such as methodological standardization and a focus on long-term studies.
我们研究了共病创伤后应激障碍（CO-PTSD）在物质使用障碍（DSM-IV/ICD-10 物质滥用或依赖，SUD）治疗中的作用。我们对 2000 年至 2011 年患有和未患有 CO-PTSD 的 SUD 患者的治疗结果研究进行了系统评价。N = 22 项研究在方法和所提供研究信息的充分性方面存在明显差异，限制了它们的可比性。值得注意的是，未发现 CO-PTSD 对报告的 SUD 治疗结果有负面影响的一致迹象。除了 CO-PTSD，我们指出了可能需要更好理解的其他潜在效应修饰因素。最后，我们强调了未来研究的要求，如方法标准化和关注长期研究。
