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应用对比增强多排螺旋 CT 对活体肝移植供者的评估-放射科医师对供者选择的影响。

Evaluation of living liver donors using contrast enhanced multidetector CT - The radiologists impact on donor selection.

机构信息

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg Str, 1, 30625, Hannover, Germany.

出版信息

BMC Med Imaging. 2012 Jul 24;12:21. doi: 10.1186/1471-2342-12-21.

DOI:10.1186/1471-2342-12-21
PMID:22828359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3427040/
Abstract

BACKGROUND

Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process.

METHODS

Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection.

RESULTS

89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume.

CONCLUSION

CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT.

摘要

背景

活体肝移植（LDLT）是治疗终末期肝病患者的一种有价值且合理的治疗方法。计算机断层扫描（CT）已被证明是供体评估过程中的重要工具。本研究旨在评估 CT 在供体选择过程中的意义。

方法

1999 年 5 月至 2010 年 10 月期间，170 名候选供体接受了双期 CT 检查。我们回顾性分析了 CT 和肝体积测量的结果，并评估了被拒绝的原因。

结果

89 名候选者接受了部分肝切除术（52.4%）。根据肝 CT 和体积测量的结果，有 22 名候选者被排除为供体（占病例的 31%）。原因包括脂肪肝（n=9）、血管解剖变异（n=4）、偶然发现的血管瘤和局灶性结节性增生（n=1）以及体积小（n=5）或体积过大（n=5）的供体。

结论

基于 CT 的肝脏成像与专用软件相结合，在 LDLT 候选者的评估过程中发挥着关键作用。它可能占 LDLT 禁忌证的 1/3 左右。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/70410888155d/1471-2342-12-21-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/1f76f1e9dff5/1471-2342-12-21-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/9f5dca92fb0f/1471-2342-12-21-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/a30ab86f4cde/1471-2342-12-21-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/1230b5bdec77/1471-2342-12-21-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/70410888155d/1471-2342-12-21-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/1f76f1e9dff5/1471-2342-12-21-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/9f5dca92fb0f/1471-2342-12-21-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/a30ab86f4cde/1471-2342-12-21-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/1230b5bdec77/1471-2342-12-21-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b02a/3427040/70410888155d/1471-2342-12-21-5.jpg

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