The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.
Lancet. 2012 Nov 24;380(9856):1860-6. doi: 10.1016/S0140-6736(12)61154-4. Epub 2012 Jul 23.
The unprecedented, successful collaborative international effort to provide universal access to HIV care, including effective antiretroviral therapy, has reached a crucial point. Global economic downturn, changing donor priorities, and competing priorities in the health sector threaten the target of provision of 15 million people with HIV/AIDS with treatment by 2015, as agreed by the UN General Assembly. This aspiration has received added impetus from the finding that treatment prevents transmission by reduction of infectiousness of patients. In this report we critically review success thus far and examine efforts to optimise delivery of HIV care including antiretroviral therapy in low-income and middle-income countries for four main domains: treatment strategy, drug dosing, monitoring, and service delivery.
空前的、成功的国际合作努力，为包括有效抗逆转录病毒治疗在内的艾滋病护理提供了普遍可及性，目前已进入一个关键阶段。全球经济下滑、捐助方优先事项的变化以及卫生部门其他优先事项，对到 2015 年为 1500 万艾滋病毒/艾滋病患者提供治疗的目标构成了威胁，这是联合国大会商定的目标。人们发现，治疗通过降低患者的传染性，可以预防传播，这一发现为实现这一愿望增添了动力。在本报告中，我们批判性地回顾了迄今为止的成功，并探讨了在中低收入国家优化艾滋病毒护理（包括抗逆转录病毒治疗）的努力，主要集中在四个方面：治疗策略、药物剂量、监测和服务提供。
