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流行病学、应对措施及未来方向:越南病毒性肝炎与艾滋病毒合并感染的隐性流行

Epidemiology, responses, and way forward: the silent epidemic of viral hepatitis and HIV coinfection in Vietnam.

作者信息

Sereno Leandro, Mesquita Fabio, Kato Masaya, Jacka David, Nguyen Thi Thuy Van, Nguyen Thien Nga

机构信息

1World Health Organization Vietnam Country Office, Hanoi, Vietnam.

出版信息

J Int Assoc Physicians AIDS Care (Chic). 2012 Sep-Oct;11(5):311-20. doi: 10.1177/1545109712453939. Epub 2012 Jul 24.

DOI:10.1177/1545109712453939
PMID:22828983
Abstract

Viral hepatitis is a disease of great concern to public health that is now met by a favorable momentum to combat the global epidemic. This article is intended to highlight the importance of viral hepatitis in the Vietnam population as well in the group of people living with HIV/AIDS (PLWHA). We reviewed available data on epidemiology and response on hepatitis B virus (HBV) and hepatitis C virus (HCV) and HIV coinfection in Vietnam. The hepatitis B surface antigen (HBsAg) prevalence in the general population ranged from 5.7% to 24.7%. The anti-HCV prevalence ranged from 0.38% to 4.3% in the general population, while among people who inject drugs (PWIDs) it ranged from 31% to 97.2%. The HBV prevalence among PLWHA is similar to the general population, while HCV/HIV coinfection is concentrated in some groups. Anti-HCV prevalence among HIV-infected PWIDs can be as high as 98.5%. Developing policies for diagnosis and treatment of chronic HBV and HCV infections are critical priorities in order to prevent clinical progression to cirrhosis and liver cancer.

摘要

病毒性肝炎是一种备受公共卫生关注的疾病,目前全球抗击该流行病的态势良好。本文旨在强调病毒性肝炎在越南人群以及艾滋病毒/艾滋病感染者群体中的重要性。我们回顾了越南关于乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)以及HIV合并感染的流行病学和应对措施的现有数据。一般人群中乙肝表面抗原(HBsAg)流行率在5.7%至24.7%之间。一般人群中抗-HCV流行率在0.38%至4.3%之间,而在注射吸毒者中则在31%至97.2%之间。艾滋病毒/艾滋病感染者中的HBV流行率与一般人群相似,而HCV/HIV合并感染集中在某些群体中。艾滋病毒感染的注射吸毒者中的抗-HCV流行率可高达98.5%。制定慢性HBV和HCV感染的诊断和治疗政策是预防临床进展为肝硬化和肝癌的关键优先事项。

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