Stanford Richard F J, Thomas Stephen A
Royal Derby Hospital, Derby Hospitals NHS Foundation Trust, Uttoxeter Road, Derby DE22 3NE, UK.
Case Rep Urol. 2012;2012:864741. doi: 10.1155/2012/864741. Epub 2012 Jul 8.
We present a case of a 51-year-old gentleman, previously diagnosed with high-grade superficial transitional cell carcinoma of the bladder and treated with intravesical mitomycin C and BCG, who developed serial recurrences in the prostatic urethra. This was resected and treated further with intraurethral mitomycin-C gel. He subsequently developed an almost impassable distal penile urethral stricture, corresponding to the site of penile clamp application which we hypothesise is secondary to a combination of the mitomycin-C gel and penile clamp pressure.
我们报告一例51岁男性患者,此前被诊断为膀胱高级别浅表性移行细胞癌,接受了膀胱内丝裂霉素C和卡介苗治疗,该患者前列腺尿道出现了一系列复发。对其进行了切除,并进一步采用尿道内丝裂霉素C凝胶治疗。随后,他出现了几乎无法通过的阴茎远端尿道狭窄,这与阴茎夹应用部位相对应,我们推测这是丝裂霉素C凝胶和阴茎夹压力共同作用的结果。