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[切尔诺贝利原子能电站周边10公里区域内小鼠的遗传效应]

[Genetic effects in mice exposed to the 10-km area around the Chernobyl Atomic Energy Station].

作者信息

Pomerantseva M D, Chekhovich A V, Ramaiĭa L K, Shevchenko V A, Shaks A I, Lobaneva N V

出版信息

Genetika. 1990 Oct;26(10):1870-5.

PMID:2283055
Abstract

Mice (CBAxC57BL) F of both sexes were exposed within the 10 km zone of Chernobyl nuclear power station. Genetic damage of phone chronic effect of increased radiation in exposed adult mice and in the course of embryogenesis was studied. The total absorbed radiation doses in testes varied from 1.85 to 0.42 Gy in embryos and from 3.4 to 2.7 Gy in adult males. Increase of dominant lethal mutations (DLM) and abnormal sperm heads (ASH) was only observed right after the end of exposure of adult males. The yield of reciprocal translocations (RT) in these males was relatively low. Among the males exposed at the stage of early embryogenesis, 4 heterozygotes for RT were revealed. In other males of this group the RT yield was low.

摘要

将(CBAxC57BL)品系的雌雄小鼠置于切尔诺贝利核电站10公里区域内。研究了辐射增加对成年小鼠和胚胎发育过程中细胞慢性影响的遗传损伤。胚胎睾丸中的总吸收辐射剂量在1.85至0.42 Gy之间,成年雄性小鼠的总吸收辐射剂量在3.4至2.7 Gy之间。仅在成年雄性小鼠暴露结束后,才观察到显性致死突变(DLM)和异常精子头(ASH)的增加。这些雄性小鼠中相互易位(RT)的发生率相对较低。在早期胚胎发育阶段暴露的雄性小鼠中,发现了4只RT杂合子。该组其他雄性小鼠的RT发生率较低。

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