Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea.
Ann Nutr Metab. 2012;61(1):47-56. doi: 10.1159/000339262. Epub 2012 Jul 20.
BACKGROUND/AIMS: To evaluate the effects of medical nutrition therapy (MNT) on body composition and metabolic syndrome (MetS) components in premenopausal Korean women with a body mass index ≥23.
Participants (n = 160) were classified into MetS (n = 44) or non-MetS (n = 116) groups based on the criteria proposed by the revised National Cholesterol Education Program-Adult Treatment Panel III and the International Diabetes Federation classification. Anthropometric and dietary assessments and blood analyses were performed for all participants prior to and following 12 weeks of MNT.
Following MNT, body fat decreased in both groups by roughly 11% (p < 0.001), and the number of participants meeting the criteria for MetS thus decreased from 44 to 19 (56.8%). Mean waist circumference (WC), blood pressure (BP), plasma triglyceride (TG) and blood glucose levels decreased in the MetS group (p < 0.001). Body fat reduction in the MetS group was correlated with changes in WC (r = 0.584), systolic BP (r = 0.451), diastolic BP (r = 0.429) and plasma TG (r = 0.488) levels after adjusting for covariates (p < 0.05).
Body fat reduction and MetS component improvement was achieved by MNT in overweight women. Changes in MetS components appear to be related to body fat reduction. MNT should focus on body fat reduction when used as a primary prevention for MetS.
背景/目的：评估医学营养疗法（MNT）对身体成分和代谢综合征（MetS）成分的影响，纳入的研究对象为身体质量指数（BMI）≥23 的绝经前韩国女性。
根据修订后的国家胆固醇教育计划-成人治疗小组 III 和国际糖尿病联合会分类标准，将参与者（n=160）分为 MetS（n=44）或非 MetS（n=116）组。所有参与者在接受 12 周 MNT 之前和之后进行人体测量和饮食评估以及血液分析。
MNT 后，两组的体脂均减少了约 11%（p<0.001），因此符合 MetS 标准的参与者人数从 44 人减少到 19 人（56.8%）。MetS 组的平均腰围（WC）、血压（BP）、血浆甘油三酯（TG）和血糖水平均降低（p<0.001）。MetS 组的体脂减少与 WC（r=0.584）、收缩压（r=0.451）、舒张压（r=0.429）和血浆 TG（r=0.488）水平的变化相关（调整协变量后，p<0.05）。
超重女性通过 MNT 实现了体脂减少和 MetS 成分改善。MetS 成分的变化似乎与体脂减少有关。MNT 作为 MetS 的主要预防措施时，应侧重于减少体脂。
