Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle-Perret-Gentil 4, CH-1211, Geneva 14, Switzerland.
Osteoporos Int. 2013 Mar;24(3):867-76. doi: 10.1007/s00198-012-2045-3. Epub 2012 Jul 26.
This controlled intervention study in hospitalized oldest old adults showed that a multifactorial fall-and-fracture risk assessment and management program, applied in a dedicated geriatric hospital unit, was effective in improving fall-related physical and functional performances and the level of independence in activities of daily living in high-risk patients.
Hospitalization affords a major opportunity for interdisciplinary cooperation to manage fall-and-fracture risk factors in older adults. This study aimed at assessing the effects on physical performances and the level of independence in activities of daily living (ADL) of a multifactorial fall-and-fracture risk assessment and management program applied in a geriatric hospital setting.
A controlled intervention study was conducted among 122 geriatric inpatients (mean ± SD age, 84 ± 7 years) admitted with a fall-related diagnosis. Among them, 92 were admitted to a dedicated unit and enrolled into a multifactorial intervention program, including intensive targeted exercise. Thirty patients who received standard usual care in a general geriatric unit formed the control group. Primary outcomes included gait and balance performances and the level of independence in ADL measured 12 ± 6 days apart. Secondary outcomes included length of stay, incidence of in-hospital falls, hospital readmission, and mortality rates.
Compared to the usual care group, the intervention group had significant improvements in Timed Up and Go (adjusted mean difference [AMD] = -3.7s; 95 % CI = -6.8 to -0.7; P = 0.017), Tinetti (AMD = -1.4; 95 % CI = -2.1 to -0.8; P < 0.001), and Functional Independence Measure (AMD = 6.5; 95 %CI = 0.7-12.3; P = 0.027) test performances, as well as in several gait parameters (P < 0.05). Furthermore, this program favorably impacted adverse outcomes including hospital readmission (hazard ratio = 0.3; 95 % CI = 0.1-0.9; P = 0.02).
A multifactorial fall-and-fracture risk-based intervention program, applied in a dedicated geriatric hospital unit, was effective and more beneficial than usual care in improving physical parameters related to the risk of fall and disability among high-risk oldest old patients.
本对照干预研究旨在评估在老年医院病房中应用多因素跌倒/骨折风险评估和管理方案对高风险老年患者的跌倒相关身体和功能表现以及日常生活活动自理能力的影响。
对 122 名因跌倒相关诊断而住院的老年患者(平均年龄 ± 标准差,84 ± 7 岁)进行对照干预研究。其中 92 名患者入住专门病房并接受多因素干预方案,包括强化靶向锻炼。30 名在普通老年病房接受标准常规护理的患者作为对照组。主要结局指标为 12 ± 6 天内的步态和平衡表现以及日常生活活动自理能力。次要结局指标包括住院时间、院内跌倒发生率、医院再入院率和死亡率。
与常规护理组相比,干预组的计时起立行走测试(调整后的平均差异 [AMD] = -3.7s;95%置信区间 = -6.8 至 -0.7;P = 0.017)、Tinetti 测试(AMD = -1.4;95%置信区间 = -2.1 至 -0.8;P < 0.001)和功能独立性测量(AMD = 6.5;95%置信区间 = 0.7-12.3;P = 0.027)测试表现均有显著改善,且多项步态参数也有显著改善(P < 0.05)。此外,该方案还降低了医院再入院率(风险比 = 0.3;95%置信区间 = 0.1-0.9;P = 0.02)等不良结局的发生风险。
在老年医院病房中应用基于多因素跌倒/骨折风险的干预方案比常规护理更有效,可改善高风险高龄患者的跌倒和残疾相关身体参数。