Endo Toshiya, Sanpei Sugako, Komatsuzaki Akira, Endo Saori, Takakuwa Akiko, Oka Kenji
Orthodontic Dentistry, The Nippon Dental University Niigata Hospital, 1-8 Hamaura-cho, Chuo-ku, Niigata, 951-8580, Japan,
Odontology. 2013 Jul;101(2):216-21. doi: 10.1007/s10266-012-0080-3. Epub 2012 Jul 26.
The aim of this study was to explore the patterns of tooth agenesis in Japanese orthodontic patients with bilateral agenesis of mandibular second premolars. A total of 80 Japanese orthodontic patients with 2 congenitally missing mandibular second premolars were selected as the subjects of this study (experimental group). Another 80 individuals without bilateral agenesis of mandibular second premolars were collected for comparison (control group). The 2 groups were matched with regard to sex. Radiographs, dental casts and records of medical and/or dental treatment were used to identify tooth agenesis. The Chi-square test, odds ratio, and test for equality were used to make statistical comparisons. The prevalence rates of other types of tooth agenesis were significantly higher in the experimental group than in the control group. The occurrence of agenesis of maxillary and mandibular lateral incisors and third molars, and maxillary second premolars was also significantly higher in the experimental group than in the control group. Significantly increased prevalence rates of symmetrical tooth agenesis, with third molars included, and oligodontia were observed in the experimental group. Japanese subjects with bilateral agenesis of mandibular second premolars are at significantly high risk of agenesis of other types of permanent teeth, symmetrical tooth agenesis and oligodontia.
本研究的目的是探究日本正畸患者双侧下颌第二前磨牙先天缺失的牙胚发育模式。本研究选取了80例双侧先天性缺失下颌第二前磨牙的日本正畸患者作为研究对象（实验组）。另外收集了80例无双侧下颌第二前磨牙先天缺失的个体作为对照（对照组）。两组在性别上进行了匹配。通过X光片、石膏模型以及医疗和/或牙科治疗记录来确定牙胚发育异常情况。采用卡方检验、优势比和均等性检验进行统计学比较。实验组中其他类型牙胚发育异常的患病率显著高于对照组。实验组中上颌和下颌侧切牙、第三磨牙以及上颌第二前磨牙先天缺失的发生率也显著高于对照组。在实验组中观察到包括第三磨牙在内的对称性牙胚发育异常和少牙畸形的患病率显著增加。双侧下颌第二前磨牙先天缺失的日本受试者患其他类型恒牙先天缺失、对称性牙胚发育异常和少牙畸形的风险显著较高。
