放射性标记的脱蛋白黏蛋白SM3，用于卵巢肿瘤免疫闪烁显像的单克隆抗体。
Radiolabelled stripped mucin, SM3, monoclonal antibody for immunoscintigraphy of ovarian tumours.
作者信息
Granowska M, Mather S J, Jobling T, Naeem M, Burchell J, Taylor-Papadimitriou J, Shepherd J, Britton K E
机构信息
Department of Nuclear Medicine, St. Bartholomew's Hospital, London, England.
出版信息
Int J Biol Markers. 1990 Apr-Jun;5(2):89-96. doi: 10.1177/172460089000500208.
PMID:2283483
Abstract
A new monoclonal antibody, SM3, against stripped mucin core protein has been evaluated for the radioimmunoscintigraphy of ovarian cancer. It was radiolabelled with In-111, I-123 and Tc-99m and results showed a sensitivity of 95%, 100% and 100% and an accuracy of 73%, 86% and 100% for malignancy; respectively.
摘要
一种针对脱糖粘蛋白核心蛋白的新型单克隆抗体SM3已用于卵巢癌的放射免疫闪烁显像评估。它分别用铟-111、碘-123和锝-99m进行放射性标记，结果显示对恶性肿瘤的敏感性分别为95%、100%和100%，准确性分别为73%、86%和100%。
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