Weinecke A
Hellmuth-Ulrici-Klinik, Bezirkskrankenhaus für Lungenkrankheiten und Tuberkulose der Haupstadt der DDR, Sommerfeld.
Z Erkr Atmungsorgane. 1989;173(1):63-7.
The efficacy of the therapy of tuberculous lymphadenitis using two drugs with bactericidal activity is described. In this localization, the tuberculous process implies tubercle bacilli only in limited quantity, and thus, in contrast to the requirements and recommendations for the treatment of pulmonary tuberculosis, the application of only two drugs with bactericidal activity is sufficient. The treatment of 128 patients with histologically confirmed tuberculous lymphadenitis consisted in daily application of isoniazid and rifampicin during 4 to 6 weeks, followed by an intermittent treatment with the same drugs for 6 to 9 months. The follow-up period was 7.5 years. Complete involution of the diseased lymph nodes was obtained in two thirds of the patients, partial involution in the remaining third. In one patient, a relapse occurred. The indications of this regimen are discussed.
描述了使用两种具有杀菌活性的药物治疗结核性淋巴结炎的疗效。在这种病变部位，结核病变仅意味着存在数量有限的结核杆菌，因此，与治疗肺结核的要求和建议相反，仅应用两种具有杀菌活性的药物就足够了。对128例经组织学确诊为结核性淋巴结炎的患者进行治疗，方法是在4至6周内每日服用异烟肼和利福平，随后用相同药物进行6至9个月的间歇治疗。随访期为7.5年。三分之二的患者病变淋巴结完全消退，其余三分之一部分消退。有1例患者复发。讨论了该治疗方案的适应证。
