Section of Vascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.
J Ultrasound Med. 2012 Aug;31(8):1169-74. doi: 10.7863/jum.2012.31.8.1169.
Carotid duplex sonography is the primary tool for surveillance after carotid artery stenting, but the course of sonographic velocities over time after successful stenting is unclear. The purpose of this study was to describe carotid duplex sonographic velocity parameters after successful carotid artery stenting and to determine the predictors of poststent sonographic velocities.
We queried institutional carotid stent and noninvasive vascular laboratory databases for internal carotid artery stents placed between January 2004 and June 2007. We included patients with stenosis of 20% or less on completion angiograms who had carotid duplex sonography within 30 days before and 7 days after stenting. The prestent peak systolic velocity (PSV), end-diastolic velocity (EDV), internal-to-common carotid artery PSV ratio, contralateral internal carotid artery velocities, stent type, open- versus closed-cell stent design, and days of follow-up were tested as potential predictors of poststent velocities.
Eighty-two of 498 patients met inclusion criteria. The mean PSV and PSV ratio decreased from 423.6 cm/s and 7.1 before stenting to 98.5 cm/s and 1.3 after stenting (both P < .001). During a median follow-up of 370 days, poststent velocities remained stable. All poststent velocities (PSV, EDV, and PSV ratio) were dependent on prestent ipsilateral and contralateral velocities. The poststent EDV was dependent on the type of stent. The upper range for 0% to 20% stenosis in the stented internal carotid artery was a PSV of 141 cm/s, an EDV of 42 cm/s, and a PSV ratio of 2.1 or lower.
With a median follow-up of 1 year, the PSV and PSV ratio remained stable over time in successfully stented carotid arteries. Deviations in sonographic parameters after initial poststent carotid duplex sonography should prompt an investigation for possible in-stent restenosis.
颈动脉双功能超声是颈动脉支架置入术后监测的主要手段,但成功支架置入后超声速度随时间的变化过程尚不清楚。本研究的目的是描述颈动脉支架置入术后颈动脉双功能超声速度参数,并确定支架置入后超声速度的预测因素。
我们在 2004 年 1 月至 2007 年 6 月期间查询了机构内颈动脉支架和无创血管实验室数据库,纳入了在支架置入术完成血管造影显示狭窄程度<20%的患者,并在支架置入术前 30 天内和术后 7 天内行颈动脉双功能超声检查。检测支架置入前的峰值收缩期速度(PSV)、舒张末期速度(EDV)、颈内动脉与颈总动脉 PSV 比值、对侧颈内动脉速度、支架类型、开环与闭环支架设计以及随访天数,作为支架置入后速度的潜在预测因素。
82 例 498 例患者符合纳入标准。PSV 和 PSV 比值从支架置入前的 423.6cm/s 和 7.1 分别降至支架置入后的 98.5cm/s 和 1.3(均 P<0.001)。在中位数为 370 天的随访期间,支架置入后的速度保持稳定。所有支架置入后的速度(PSV、EDV 和 PSV 比值)均依赖于支架置入前的同侧和对侧速度。支架置入后的 EDV 依赖于支架类型。支架置入的颈内动脉 0%~20%狭窄的上限为 PSV 为 141cm/s、EDV 为 42cm/s、PSV 比值为 2.1 或更低。
在中位数为 1 年的随访期间,成功支架置入的颈动脉 PSV 和 PSV 比值随时间保持稳定。支架置入后初始颈动脉双功能超声检查后出现的超声参数偏差应提示可能存在支架内再狭窄。