Blakey Brittony L, Gratrix Max L
Department of Dermatology, Walter Reed Army Medical Center, Washington, DC 20307, USA.
Cutis. 2012 Jun;89(6):266-8.
We report 2 cases of adolescents who developed follicular mucinosis following cutaneous infections. A 17-year-old adolescent boy was evaluated for a 2-week history of erythematous papules and plaques on his face and neck. One month prior to presentation a culture was taken that was positive for methicillin-sensitive Staphylococcus aureus-associated impetigo. Biopsies from 2 representative lesions demonstrated follicular mucinosis without evidence of folliculotropism or T cell gene rearrangements. A separate case involved a 17-year-old adolescent girl who presented with an edematous plaque on her right preauricular region and scattered erythematous papules and small annular plaques over her face 2 weeks following a herpes simplex virus type 2 (HHV-2) infection. on her face. Biopsy showed follicular mucinosis without evidence of epidermotropism or lymphocyte atypia. There was no herpesvirus cytopathic effect. The first case rapidly responded to an oral prednisone taper and the second case resolved over several weeks without further treatment.
我们报告了2例青少年在皮肤感染后发生毛囊黏蛋白病的病例。一名17岁的青少年男性因面部和颈部出现红斑丘疹和斑块2周前来就诊。就诊前1个月的培养结果显示，其为甲氧西林敏感金黄色葡萄球菌相关性脓疱病阳性。取自2个代表性皮损的活检显示为毛囊黏蛋白病，无向毛囊性或T细胞基因重排的证据。另一例是一名17岁的青少年女性，在感染2型单纯疱疹病毒（HHV-2）2周后，右耳前区出现一个水肿性斑块，面部有散在的红斑丘疹和小环形斑块。活检显示为毛囊黏蛋白病，无向表皮性或淋巴细胞异型性的证据。未发现疱疹病毒细胞病变效应。第一例对口服泼尼松逐渐减量迅速起效，第二例未经进一步治疗在数周内痊愈。
