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番石榴籽仁对瑞士白化病小鼠的止泻功效。

Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice.

机构信息

Department of Microbiology, M. R. Govt Arts College, Mannargudi-614 001, Thiruvarur District, Tamilnadu, India.

出版信息

Asian Pac J Trop Med. 2012 Aug;5(8):630-3. doi: 10.1016/S1995-7645(12)60129-1.

Abstract

OBJECTIVE

To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.

METHODS

Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.

RESULTS

Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.

CONCLUSIONS

The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.

摘要

目的

研究番石榴(Mangifera indica)的醇提和水提种仁提取物对蓖麻油诱导的瑞士白化病小鼠腹泻活性的抗腹泻作用。

方法

番石榴种仁经加工后分别用酒精和水提取。采用肠道动力和粪便评分法评价提取物的抗腹泻活性。

结果

番石榴的水提和醇提物均能显著降低瑞士白化病小鼠的肠道动力和粪便评分。

结论

本研究证实了印度南部地区使用番石榴种仁治疗腹泻的传统说法。

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