Glikmanas M, Giraudet M C, Fould G
Sem Hop. 1979;55(27-30):1305-11.
Multiple metabolic factors of atherosclerosis frequently associated in the same patient proves the interest of a multifactorial treatment of atherosclerosis. In the paper the authors studied the results of the treatment with benfluorex of 1 000 patients suffering one or more metabolic risk factors. After a 3 month treatment, a highly significant and simultaneous reduction of hyperlipidemia, hyperglycemia, hyperuricemia is observed. The treatment is the more efficient that initial values are higher and that the diet is better observed. The results remain significant even in patients who have not lost weight.
动脉粥样硬化的多种代谢因素常常在同一患者身上同时出现,这证明了对动脉粥样硬化进行多因素治疗的意义。在本文中,作者研究了1000例患有一种或多种代谢风险因素的患者使用苯氟雷司治疗的结果。经过3个月的治疗,观察到高脂血症、高血糖、高尿酸血症同时显著降低。初始值越高且饮食遵守得越好,治疗效果就越显著。即使在体重未减轻的患者中,结果仍然显著。