School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
Chem Commun (Camb). 2012 Sep 14;48(71):8976-8. doi: 10.1039/c2cc33695b. Epub 2012 Jul 27.
By modulating the chelating priorities of the different directing groups in 3,5-diketo amides with the assistance from coordinating solvent, highly chemo- and enantioselective hydrogenation of the C3-carbonyls was achieved in the presence of [RuCl(benzene)(S)-SunPhos]Cl in THF.
通过在 3,5-二酮酰胺中不同导向基团的螯合优先顺序的调节，在[RuCl(苯)(S)-SunPhos]Cl 的存在下，在 THF 中实现了 C3-羰基的高化学选择性和对映选择性氢化。
