Julius Center for Health Sciences and Primary Care, Str. 6.131, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
J Gerontol A Biol Sci Med Sci. 2013 Mar;68(3):301-8. doi: 10.1093/gerona/gls161. Epub 2012 Jul 25.
A general frailty indicator could guide general practitioners (GPs) in directing their care efforts to the patients at highest risk. We investigated if a Frailty Index (FI) based on the routine health care data of GPs can predict the risk of adverse health outcomes in community-dwelling older people.
This was a retrospective cohort study with a 2-year follow-up period among all patients in an urban primary care center aged 60 and older: 1,679 patients (987 women [59%], median age, 73 years [interquartile range, 65-81]). For each patient, a baseline FI score was computed as the number of health deficits present divided by the total number of 36 deficits on the FI. Adverse health outcomes were defined as the first registered event of an emergency department (ED) or after-hours GP visit, nursing home admission, or death.
In total, 508 outcome events occurred within the sample population. Kaplan-Meier survival curves were constructed according to FI tertiles. The tertiles were able to discriminate between patients with low, intermediate, and high risk for adverse health outcomes (p value < .001). With adjustments for age, consultation gap, and sex, a one deficit increase in the FI score was associated with an increased hazard for adverse health outcomes (hazard ratio, 1.166; 95% confidence interval [CI], 1.129-1.210) and a moderate predictive ability for adverse health outcomes (c-statistic, 0.702; 95% CI, 0.680-0.724).
An FI based on International Classification of Primary Care (ICPC)-encoded routine health care data does predict the risk of adverse health outcomes in elderly population.
一般虚弱指标可以指导全科医生将护理工作重点放在风险最高的患者身上。我们研究了基于全科医生常规医疗保健数据的虚弱指数(FI)是否可以预测社区居住的老年人不良健康结果的风险。
这是一项回顾性队列研究,对城市初级保健中心所有 60 岁及以上的患者进行了为期 2 年的随访:1679 名患者(987 名女性[59%],中位年龄 73 岁[四分位距,65-81])。对于每位患者,计算基线 FI 评分,方法是将存在的健康缺陷数量除以 FI 上 36 个缺陷的总数。不良健康结果定义为首次记录到急诊科(ED)或下班后全科医生就诊、疗养院入院或死亡的事件。
在整个样本人群中,共发生 508 例不良健康结果事件。根据 FI 三分位值绘制 Kaplan-Meier 生存曲线。三分位值能够区分低、中、高不良健康结果风险的患者(p 值<.001)。在调整年龄、咨询间隔和性别后,FI 评分增加一个缺陷与不良健康结果的风险增加相关(危险比,1.166;95%置信区间[CI],1.129-1.210),并且对不良健康结果具有中等预测能力(C 统计量,0.702;95%CI,0.680-0.724)。
基于国际初级保健分类(ICPC)编码常规医疗保健数据的 FI 确实可以预测老年人群不良健康结果的风险。