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在治疗股骨颈移位骨折时,使用非骨水泥型半髋关节置换术比骨水泥型半髋关节置换术后需要更多的再次手术:一项基于国家登记处11,116例半髋关节置换术的观察性研究。

More re-operations after uncemented than cemented hemiarthroplasty used in the treatment of displaced fractures of the femoral neck: an observational study of 11,116 hemiarthroplasties from a national register.

作者信息

Gjertsen J-E, Lie S A, Vinje T, Engesæter L B, Hallan G, Matre K, Furnes O

机构信息

Haukeland University Hospital, Department of Orthopaedic Surgery, N-5021 Bergen, Norway.

出版信息

J Bone Joint Surg Br. 2012 Aug;94(8):1113-9. doi: 10.1302/0301-620X.94B8.29155.

Abstract

Using data from the Norwegian Hip Fracture Register, 8639 cemented and 2477 uncemented primary hemiarthroplasties for displaced fractures of the femoral neck in patients aged > 70 years were included in a prospective observational study. A total of 218 re-operations were performed after cemented and 128 after uncemented procedures. Survival of the hemiarthroplasties was calculated using the Kaplan-Meier method and hazard rate ratios (HRR) for revision were calculated using Cox regression analyses. At five years the implant survival was 97% (95% confidence interval (CI) 97 to 97) for cemented and 91% (95% CI 87 to 94) for uncemented hemiarthroplasties. Uncemented hemiarthroplasties had a 2.1 times increased risk of revision compared with cemented prostheses (95% confidence interval 1.7 to 2.6, p < 0.001). The increased risk was mainly caused by revisions for peri-prosthetic fracture (HRR = 17), aseptic loosening (HRR = 17), haematoma formation (HRR = 5.3), superficial infection (HRR = 4.6) and dislocation (HRR = 1.8). More intra-operative complications, including intra-operative death, were reported for the cemented hemiarthroplasties. However, in a time-dependent analysis, the HRR for re-operation in both groups increased as follow-up increased. This study showed that the risk for revision was higher for uncemented than for cemented hemiarthroplasties.

摘要

利用挪威髋部骨折登记处的数据,对年龄大于70岁的股骨颈移位骨折患者进行的8639例骨水泥型和2477例非骨水泥型初次半髋关节置换术纳入了一项前瞻性观察研究。骨水泥型手术后共进行了218次再次手术,非骨水泥型手术后进行了128次。采用Kaplan-Meier法计算半髋关节置换术的生存率,并采用Cox回归分析计算翻修的风险率比(HRR)。5年时,骨水泥型半髋关节置换术的植入物生存率为97%(95%置信区间(CI)97至97),非骨水泥型为91%(95%CI 87至94)。与骨水泥型假体相比,非骨水泥型半髋关节置换术的翻修风险增加了2.1倍(95%置信区间1.7至2.6,p<0.001)。风险增加主要是由于假体周围骨折翻修(HRR=17)、无菌性松动(HRR=17)、血肿形成(HRR=5.3)、浅表感染(HRR=4.6)和脱位(HRR=1.8)。骨水泥型半髋关节置换术报告了更多的术中并发症,包括术中死亡。然而,在时间依赖性分析中,两组再次手术的HRR均随随访时间增加而增加。本研究表明,非骨水泥型半髋关节置换术的翻修风险高于骨水泥型。

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