Gjertsen J-E, Lie S A, Vinje T, Engesæter L B, Hallan G, Matre K, Furnes O
Haukeland University Hospital, Department of Orthopaedic Surgery, N-5021 Bergen, Norway.
J Bone Joint Surg Br. 2012 Aug;94(8):1113-9. doi: 10.1302/0301-620X.94B8.29155.
Using data from the Norwegian Hip Fracture Register, 8639 cemented and 2477 uncemented primary hemiarthroplasties for displaced fractures of the femoral neck in patients aged > 70 years were included in a prospective observational study. A total of 218 re-operations were performed after cemented and 128 after uncemented procedures. Survival of the hemiarthroplasties was calculated using the Kaplan-Meier method and hazard rate ratios (HRR) for revision were calculated using Cox regression analyses. At five years the implant survival was 97% (95% confidence interval (CI) 97 to 97) for cemented and 91% (95% CI 87 to 94) for uncemented hemiarthroplasties. Uncemented hemiarthroplasties had a 2.1 times increased risk of revision compared with cemented prostheses (95% confidence interval 1.7 to 2.6, p < 0.001). The increased risk was mainly caused by revisions for peri-prosthetic fracture (HRR = 17), aseptic loosening (HRR = 17), haematoma formation (HRR = 5.3), superficial infection (HRR = 4.6) and dislocation (HRR = 1.8). More intra-operative complications, including intra-operative death, were reported for the cemented hemiarthroplasties. However, in a time-dependent analysis, the HRR for re-operation in both groups increased as follow-up increased. This study showed that the risk for revision was higher for uncemented than for cemented hemiarthroplasties.
利用挪威髋部骨折登记处的数据,对年龄大于70岁的股骨颈移位骨折患者进行的8639例骨水泥型和2477例非骨水泥型初次半髋关节置换术纳入了一项前瞻性观察研究。骨水泥型手术后共进行了218次再次手术,非骨水泥型手术后进行了128次。采用Kaplan-Meier法计算半髋关节置换术的生存率,并采用Cox回归分析计算翻修的风险率比(HRR)。5年时,骨水泥型半髋关节置换术的植入物生存率为97%(95%置信区间(CI)97至97),非骨水泥型为91%(95%CI 87至94)。与骨水泥型假体相比,非骨水泥型半髋关节置换术的翻修风险增加了2.1倍(95%置信区间1.7至2.6,p<0.001)。风险增加主要是由于假体周围骨折翻修(HRR=17)、无菌性松动(HRR=17)、血肿形成(HRR=5.3)、浅表感染(HRR=4.6)和脱位(HRR=1.8)。骨水泥型半髋关节置换术报告了更多的术中并发症,包括术中死亡。然而,在时间依赖性分析中,两组再次手术的HRR均随随访时间增加而增加。本研究表明,非骨水泥型半髋关节置换术的翻修风险高于骨水泥型。