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结膜罕见孤立性髓外浆细胞瘤病例

An unusual occurrence of solitary extramedullary plasmacytoma in the conjunctiva.

作者信息

Jiang Jingjing, Liu Yong, Wang Fulin, Huang Yifei

机构信息

Department of Ophthalmology, Chinese PLA General Hospital, Beijing, P.R. China.

出版信息

Oncol Lett. 2012 Aug;4(2):245-246. doi: 10.3892/ol.2012.726. Epub 2012 May 22.

Abstract

The occurrence of a solitary plasmacytoma in the conjunctiva is unusual. This relatively uncommon neoplastic disorder occurs more frequently in other organs and is derived from B-lymphocytes. In the present study the case of a 17-year-old female, who had a lesion of the lower fornix conjunctiva in the left eye, is presented. The lesion was resected and the patient underwent amniotic membrane transplantation. Pathological examination of the specimen showed a plasmacytoma. Bone marrow aspirate showed that the cellularity and number of plasma cells were normal, and no myeloma cells were observed. A complete skeletal survey failed to show bony masses or osteolytic events. Following surgery, the patient was provided with a course of radiotherapy. During the follow-up period of 12 months the lesion did not recur.

摘要

结膜孤立性浆细胞瘤的发生较为罕见。这种相对不常见的肿瘤性疾病在其他器官中更常发生,起源于B淋巴细胞。本研究报告了一名17岁女性的病例,其左眼下方穹窿结膜有一处病变。病变被切除,患者接受了羊膜移植。标本的病理检查显示为浆细胞瘤。骨髓穿刺显示细胞成分和浆细胞数量正常,未观察到骨髓瘤细胞。全身骨骼检查未发现骨质肿块或溶骨病变。手术后,患者接受了一个疗程的放射治疗。在12个月的随访期内,病变未复发。

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本文引用的文献

1
Conjunctival plasmacytoma.结膜浆细胞瘤
Optometry. 2010 May;81(5):234-9. doi: 10.1016/j.optm.2009.11.006.
2
Primary eyelid plasmacytoma.
Med Oncol. 2000 Feb;17(1):74-5. doi: 10.1007/BF02826221.
3
Solitary plasmacytoma of bone and extramedullary plasmacytoma.骨孤立性浆细胞瘤和髓外浆细胞瘤。
Hematol Oncol Clin North Am. 1999 Dec;13(6):1249-57. doi: 10.1016/s0889-8588(05)70124-6.
4
Extramedullary plasmacytomas of the head and neck.头颈部髓外浆细胞瘤
Otolaryngol Head Neck Surg. 1993 Nov;109(5):877-85. doi: 10.1177/019459989310900517.

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