通过2DICAL进行胰腺癌和胃肠道癌的生物标志物发现：液相色谱和质谱的二维图像转换分析

Biomarker Discovery of Pancreatic and Gastrointestinal Cancer by 2DICAL: 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry.

作者信息

Ono Masaya, Kamita Masahiro, Murakoshi Yusuke, Matsubara Junichi, Honda Kazufumi, Miho Banno, Sakuma Tomohiro, Yamada Tesshi

机构信息

Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

出版信息

Int J Proteomics. 2012;2012:897412. doi: 10.1155/2012/897412. Epub 2012 Jul 10.

Biomarkers tested by blood sample are of great use to clinicians as they provide useful information to aid an early and accurate diagnosis. Comprehensive "omics" studies are expected to facilitate the identification of such new biomarkers, and much research is being performed in this area. Our proteomics analysis system of 2-dimensional image-converted analysis of liquid chromatography and mass spectrometry (2DICAL) has successfully identified several new blood biomarkers from the clinical blood samples of pancreatic and colorectal cancer patients.