Braun U, Trösch L, Koschwanez M, Rütten M, Hilbe M
Departement für Nutztiere, Winterthurerstrasse 260, Zurich.
Schweiz Arch Tierheilkd. 2012 Aug;154(8):331-5. doi: 10.1024/0036-7281/a000357.
This report describes an 8.8-year-old Simmental cow with squamous cell carcinoma of the reticulum and liver. The cow had calved recently and was referred to our clinic because of intractable fever, anorexia and progressive indigestion. The general condition and mental status were moderately affected and rectal temperature and respiratory rate were significantly elevated. There were no ruminal sounds and pinching of the withers consistently elicited a grunt. Serum activities of gamma glutamyl transferase, glutamate dehydrogenase and sorbitol dehydrogenase were elevated. Radiographic examination of the reticulum and ultrasonographic examination of the reticulum, liver and abdominal cavity revealed multifocal, poorly demarcated, heterogeneous and echogenic changes in the liver. Biopsy of these lesions yielded a diagnosis of squamous cell carcinoma. The cow was euthanized and a postmortem examination confirmed the diagnosis. A 15 by 15 cm neoplasm was found in the reticular wall, and histological examination showed squamous cell carcinoma. It was assumed that the reticular mass was the primary tumour, which metastasized to the liver via the portal vein.
本报告描述了一头8.8岁的西门塔尔牛，患有网胃和肝脏的鳞状细胞癌。这头牛最近产犊，因顽固性发热、厌食和进行性消化不良被转诊至我们的诊所。一般状况和精神状态受到中度影响，直肠温度和呼吸频率显著升高。瘤胃无蠕动音，捏压肩胛部时牛持续发出呼噜声。γ-谷氨酰转移酶、谷氨酸脱氢酶和山梨醇脱氢酶的血清活性升高。网胃的X线检查以及网胃、肝脏和腹腔的超声检查显示肝脏有多灶性、边界不清、不均匀且回声增强的改变。对这些病变进行活检确诊为鳞状细胞癌。这头牛实施了安乐死，尸体剖检证实了诊断。在网胃壁发现一个15×15厘米的肿瘤，组织学检查显示为鳞状细胞癌。推测网胃肿物是原发性肿瘤，通过门静脉转移至肝脏。
