Institute of Applied Physics, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Magn Reson Med. 2013 Jun;69(6):1697-702. doi: 10.1002/mrm.24439. Epub 2012 Jul 31.
MRI may be a noninvasive and alternative tool for skeletal age assessment in children, although few studies have reported on this topic. In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its validity was evaluated. MR images and their three-dimensional segmentation visualized detailed skeletal features of each bone in the hand and wrist. Skeletal age was then independently scored from the MR images by two raters, according to the Tanner-Whitehouse Japan system. The skeletal age assessed by MR rating demonstrated a strong positive correlation with chronological age. The intrarater and inter-rater reproducibilities were significantly high. These results demonstrate the validity and reliability of skeletal age assessment using MRI.
MRI 可能是一种非侵入性的、替代的儿童骨骼年龄评估工具,尽管很少有研究报道过这个话题。在本文中,我们使用一种针对儿童手和腕部成像优化的开放、紧凑的 MRI 对广泛年龄范围内的骨骼年龄进行了评估,并评估了其有效性。MR 图像及其三维分割可视化了手部和腕部每个骨骼的详细骨骼特征。然后,根据 Tanner-Whitehouse Japan 系统,由两名评分者从 MR 图像中独立对骨骼年龄进行评分。MR 评分评估的骨骼年龄与实际年龄呈强正相关。内部和外部评分者的可重复性非常高。这些结果表明 MRI 用于评估骨骼年龄的有效性和可靠性。