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首次精神病发作期间使用摇头丸和未使用摇头丸患者的症状特征。

Symptomatological features of patients with and without Ecstasy use during their first psychotic episode.

机构信息

Vincent P. Dole Dual Diagnosis Unit, Santa Chiara University Hospital, Department of Neurosciences, University of Pisa, Pisa, Italy.

出版信息

Int J Environ Res Public Health. 2012 Jul;9(7):2283-92. doi: 10.3390/ijerph9072283. Epub 2012 Jun 27.

Abstract

BACKGROUND

Ecstasy use is generally chosen by adolescents and young adults for its entactogenic properties (the production of feelings of empathy, love, and emotional closeness to others.) Despite this desired and frequently realized outcome, Ecstasy use has often resulted in the genesis of psychotic symptoms and aggressive behaviors, particularly after chronic and/or intensive use.

METHODS

To explore the negative consequences of Ecstasy use and to examine the aggressive nature oftentimes seen in many Ecstasy users we employed a case-control study model. We compared, by means of validated psychometric tests, the psychopathological symptoms (BPRS), the aggressiveness (OAS) and the social adjustment (DSM-GAF) of psychotic patients with (n = 23) and without (n = 46) recent user of Ecstasy, during their first psychotic episode and hospitalization. All 23 Ecstasy users were Ecstasy users only.

RESULTS

Almost all of the psychotic symptoms were of similar severity in both groups. Blunted affect was milder in users than in non-users, whereas hostility and aggressive behavior was significantly more severe in users than in non-users.

CONCLUSIONS

psychosis with a high level of aggressiveness and violence constitutes an important 'side-effect' that surely runs counter to the expected entactogenic action of Ecstasy. At a patient psycho-educational level, this study suggests that the use of Ecstasy may be counterproductive with respect to user expectations.

摘要

背景

摇头丸通常被青少年和年轻人选择使用,因为它具有致幻作用(产生同理心、爱和与他人情感亲近的感觉)。尽管有这种期望的结果,并且经常实现,但摇头丸的使用往往导致了精神病症状和攻击行为的产生,特别是在长期和/或密集使用后。

方法

为了探索摇头丸使用的负面影响,并研究许多摇头丸使用者通常表现出的攻击性本质,我们采用了病例对照研究模型。我们通过验证的心理测量测试比较了有(n=23)和没有(n=46)近期摇头丸使用史的精神病患者的精神病理症状(BPRS)、攻击性(OAS)和社会适应(DSM-GAF)。所有 23 名摇头丸使用者均为摇头丸单一使用者。

结果

几乎所有的精神病症状在两组中的严重程度都相似。在使用者中,迟钝的情绪比非使用者轻,而敌意和攻击行为在使用者中比非使用者严重得多。

结论

具有高攻击性和暴力程度的精神病构成了一个重要的“副作用”,这肯定与摇头丸预期的致幻作用背道而驰。在患者心理教育层面上,这项研究表明,摇头丸的使用可能与使用者的期望背道而驰。

相似文献

6
An "accidental" acute psychosis with ecstasy use.一例使用摇头丸导致的“意外”急性精神病。
J Psychoactive Drugs. 2001 Jan-Mar;33(1):95-8. doi: 10.1080/02791072.2001.10400473.

本文引用的文献

1
Update on ecstasy.摇头丸最新情况。
J Psychosoc Nurs Ment Health Serv. 2011 Apr;49(4):16-8. doi: 10.3928/02793695-20110302-03. Epub 2011 Mar 16.

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