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基于重复测量的中国儿童青少年高血压患病率及危险因素

Prevalence and risk factors of hypertension based on repeated measurements in Chinese children and adolescents.

作者信息

Meng Linghui, Liang Yajun, Liu Junting, Hu Yuehua, Yan Yinkun, Mi Jie

机构信息

Graduate School, Peking Union Medical College, Beijing 100730, China.

出版信息

Blood Press. 2013 Feb;22(1):59-64. doi: 10.3109/08037051.2012.701790. Epub 2012 Aug 2.

DOI:10.3109/08037051.2012.701790
PMID:22853559
Abstract

OBJECTIVES

This study aimed to determine the prevalence of hypertension from repeated blood pressure (BP) measurements, and examine the association between hypertension and obesity, as well as other related risk factors, in a Chinese pediatric population.

METHODS

A total of 6692 children, aged 3-18 years, were recruited in 2010. Anthropometric measurements and BP were measured using a mercury sphygmomanometer. Those with an elevated BP were screened a second or third time at 2-week intervals. "Hypertension" was defined as elevated BP on all three occasions. A self-administered questionnaire was completed.

RESULTS

The prevalence of an elevated BP was 18.2%, 5.1% and 3.1% on the first, second and third visits, respectively. The odds ratios (ORs) and 95% confidence intervals (CIs) for an elevated BP among obese children were 7.07 (5.94-8.42), 17.23 (12.63-23.52) and 20.63 (13.69-31.09), and among those with a paternal history of hypertension were 1.26 (0.98-1.61), 1.35 (0.90-2.02) and 1.80 (1.15-2.81) on each consecutive visit.

CONCLUSIONS

Repeated measurements are required to confirm the diagnosis of hypertension in children and that obesity and paternal hypertension are strongly associated with pediatric hypertension.

摘要

目的

本研究旨在通过重复测量血压来确定中国儿童人群中高血压的患病率,并研究高血压与肥胖以及其他相关危险因素之间的关联。

方法

2010年共招募了6692名3至18岁的儿童。使用汞柱式血压计测量人体测量指标和血压。血压升高的儿童每隔2周进行第二次或第三次筛查。“高血压”定义为三次测量血压均升高。完成一份自填式问卷。

结果

第一次、第二次和第三次就诊时血压升高的患病率分别为18.2%、5.1%和3.1%。肥胖儿童血压升高的比值比(OR)和95%置信区间(CI)分别为7.07(5.94 - 8.42)、17.23(12.63 - 23.52)和20.63(13.69 - 31.09),有父亲高血压病史的儿童在每次连续就诊时的比值比分别为1.26(0.98 - 1.61)、1.35(0.90 - 2.02)和1.80(1.15 - 2.81)。

结论

需要重复测量以确诊儿童高血压,并且肥胖和父亲患高血压与儿童高血压密切相关。

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