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[生理妊娠及特发性子宫内发育障碍时胎盘的形态功能特征]

[The morphofunctional characteristics of the placenta in physiological pregnancy and in idiopathic disorders of intrauterine development].

作者信息

Barkov L A, Aleshchenko I E

出版信息

Arkh Patol. 1990;52(7):35-9.

PMID:2285361
Abstract

Combined study of placentas from 43 foetuses and newborns with full duration of pregnancy (morphological, morphometrical, histoenzymatic) in intrauterine hypotrophy and idiopathic inhibition of the intrauterine development revealed a subcompensated placental failure as compared to the placenta of normotrophic children. The latter is due to decrease of organometric placenta parameters and increase of its anomalies frequency, increase of the volume of the organ afunctional parenchyma, decrease of the volume of morphological equivalents of both hormonal and transport function, non-adequate transplacental exchange because of the villous chorion immaturity and low level of the energetic supply of all placental functions. All this confirms an important role of placenta in the pathogenesis of idiopathic disturbances of the foetal intrauterine development.

摘要

对43例足月胎儿和新生儿胎盘进行联合研究(形态学、形态计量学、组织酶学),这些胎儿和新生儿存在宫内发育迟缓及特发性宫内发育抑制。研究发现,与营养正常儿童的胎盘相比,这些胎盘存在代偿不足的胎盘功能衰竭。这是由于胎盘器官测量参数降低、异常频率增加、无功能实质器官体积增大、激素和运输功能形态学等效物体积减小、绒毛膜不成熟导致经胎盘交换不充分以及所有胎盘功能的能量供应水平较低。所有这些都证实了胎盘在胎儿宫内发育特发性紊乱发病机制中的重要作用。

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