Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9105-9. doi: 10.1002/anie.201204215. Epub 2012 Jul 31.
The metal-free amination of different aldehydes is catalyzed by hypoiodite, which is generated by employing commercially available sodium percarbonate as the co-oxidant. This approach has several advantages: it is a metal-free oxidation that works under mild reaction conditions; furthermore, it has a wide substrate scope and does not give toxic by-products from the co-oxidant that is used.
次碘酸盐可以催化不同醛的无金属氨化反应，次碘酸盐是通过使用市售的过碳酸钠作为共氧化剂来生成的。该方法具有以下几个优点：它是一种无金属的氧化反应，可以在温和的反应条件下进行；此外，它具有广泛的底物范围，并且不会产生使用的共氧化剂的有毒副产物。
