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生命末期的化疗:何时停止?

Chemotherapy at the end of life: up until when?

机构信息

Servicio de Oncología Médica y Cuidados Paliativos, Hospital Universitario Marqués de Valdecilla, Avd Valdecilla s/n, 39008, Santander, Cantabria, Spain.

出版信息

Clin Transl Oncol. 2012 Sep;14(9):667-74. doi: 10.1007/s12094-012-0847-6. Epub 2012 Jul 7.

Abstract

AIM

The aim of this study is to analyze the use of CT in terminal stage cancer and the percentage of patients who received UCPD in 2009 and 2010 on the Medical Oncology and Palliative Home Care integrated service (UCPD) ward of the Marqués de Valdecilla University Hospital.

METHOD

Retrospective analysis of death rate registered on the Medical Oncology ward for 2009 and 2010 and the recorded date of the last CT given. The data are analyzed using the SPSS version 15.0 statistic package. Data were obtained from the Database Minimum Set for oncology admissions.

RESULTS

The death rate on the Medical Oncology ward is 22-24%. Total number of cases studied is 303. 47% of patients are aged 60 or younger. 81.8% (248) received active cancer treatment; of these, 138 (55.6%) in the last month, and 84 (33.8%) in the last 2 weeks. Only 66 patients out of those who died on the ward (21%) were previously sent to the UCPD.

CONCLUSIONS

Even when it is known that the majority of cancer patients become resistant to CT at the end of their lives, it is often given to patients of all ages. The request for palliative care is rare and often late.

摘要

目的

本研究旨在分析 2009 年和 2010 年在马尔凯斯·德瓦尔德西利亚大学医院综合肿瘤医学和姑息家庭护理(UCPD)病房接受 UCPD 的终末期癌症患者的 CT 使用情况和 UCPD 使用率。

方法

对 2009 年和 2010 年肿瘤医学病房的死亡率和最后一次 CT 记录日期进行回顾性分析。使用 SPSS 版本 15.0 统计软件包对数据进行分析。数据来自肿瘤学入院数据库最小数据集。

结果

肿瘤医学病房的死亡率为 22-24%。研究的总病例数为 303 例。47%的患者年龄在 60 岁或以下。81.8%(248 例)接受了积极的癌症治疗;其中 138 例(55.6%)在最后一个月,84 例(33.8%)在最后两周。在病房死亡的 66 名患者中(21%)只有 66 名患者之前被送往 UCPD。

结论

尽管人们已经知道大多数癌症患者在生命的最后阶段对 CT 产生耐药性,但 CT 仍经常用于各个年龄段的患者。对姑息治疗的需求很少,而且往往很晚。

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