Masoodi Ibrahim, Alsayari Khalid
Ibrahim Masoodi, Division of Gastroenterology and Hepatology, King Abdul Aziz Specialist Hospital, Taif 21944, Saudi Arabia.
World J Hepatol. 2012 Jul 27;4(7):234-6. doi: 10.4254/wjh.v4.i7.234.
We report progressive painless jaundice in a 39 year old female with a suspicion of metastatic liver disease on ultrasound and computed tomography scan of the abdomen. Although the most frequent liver lesions are liver metastasis because of dual blood supply of the liver and the impact of hormones, the index case proved to have acute autoimmune hepatitis (AIH) after liver biopsy was undertaken. AIH, an unresolving inflammation of liver, occurs predominantly among females worldwide. It may present acutely and even fulminant hepatitis has been described. The index case had a dramatic response to steroid treatment with total recovery and complete resolution of liver lesions. She is clinically fine and has been regularly attending our clinic for the last year. To our knowledge from a Medline search, this is the first report where AIH was seen to mimic metastatic liver disease.
我们报告了一名39岁女性出现进行性无痛性黄疸，腹部超声和计算机断层扫描怀疑有肝转移瘤。尽管由于肝脏的双重血液供应和激素的影响，最常见的肝脏病变是肝转移瘤，但该病例在进行肝活检后被证实为急性自身免疫性肝炎（AIH）。AIH是一种无法缓解的肝脏炎症，在全球范围内主要发生于女性。它可能急性发作，甚至有暴发性肝炎的描述。该病例对类固醇治疗有显著反应，完全康复且肝脏病变完全消退。她临床状况良好，在过去一年中定期到我们诊所就诊。据我们通过医学文献数据库检索所知，这是首例AIH被发现酷似肝转移瘤的报告。
