Parente Joana, Mathurdas Palmira, Wandschneider Luísa, Aranha João, Siopa Luís
Serviços de Dermatologia e de Medicina Interna 2, Hospital Distrital de Santarém, Santarém, Portugal.
Acta Med Port. 2011 Dec;24 Suppl 3:719-24. Epub 2011 Dec 31.
The overlap syndromes are characterized by the occurrence in the same patient of two or more autoimmune diseases. The overlap syndrome between scleroderma and polymyositis is rare. We describe a case of a 58-year-old woman in which the clinical expression, the effect of therapy and the evolution, support the concept that this syndrome is a distinct clinical entity in the spectrum of autoimmune disease.
重叠综合征的特征是同一患者出现两种或更多自身免疫性疾病。硬皮病和多发性肌炎之间的重叠综合征较为罕见。我们描述了一例58岁女性病例,其临床表现、治疗效果及病情演变均支持这一综合征是自身免疫性疾病谱中一种独特临床实体的观点。