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头颈部恶性肿瘤的个体化模板和 CT 引导下 125I 种子植入的数字模型。

A digital model individual template and CT-guided 125I seed implants for malignant tumors of the head and neck.

机构信息

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, PR China.

出版信息

J Radiat Res. 2012 Nov 1;53(6):973-7. doi: 10.1093/jrr/rrs046. Epub 2012 Aug 1.

Abstract

To enhance the accuracy of radioactive seed implants in the head and neck, a digital model individual template, containing information simultaneously on needle pathway and facial features, was designed to guide implantation with CT imaging. Thirty-one patients with recurrent and local advanced malignant tumors of head and neck after prior surgery and radiotherapy were involved in this study. Before (125)I implants, patients received CT scans based on 0.75mm thickness. And the brachytherapy treatment planning system (BTPS) software was used to make the implantation plan based on the CT images. Mimics software and Geomagic software were used to read the data containing CT images and implantation plan, and to design the individual template. Then the individual template containing the information of needle pathway and face features simultaneously was made through rapid prototyping (RP) technique. All patients received (125)I seeds interstitial implantation under the guide of the individual template and CT. The individual templates were positioned easily and accurately, and were stable. After implants, treatment quality evaluation was made by CT and TPS. The seeds and dosages distribution (D(90),V(100),V(150)) were well meet the treatment requirement. Clinical practice confirms that this approach can facilitate easier and more accurate implantation.

摘要

为了提高头颈部放射性粒子植入的准确性,设计了一种数字个体化模板,该模板同时包含针道和面部特征信息,用于 CT 成像引导植入。本研究纳入了 31 例头颈部复发性和局部晚期恶性肿瘤患者,这些患者均在先前的手术和放疗后复发。在(125)I 植入之前,患者接受了基于 0.75mm 层厚的 CT 扫描。然后,使用近距离治疗计划系统(BTPS)软件基于 CT 图像制定植入计划。 Mimics 软件和 Geomagic 软件用于读取包含 CT 图像和植入计划的数据,并设计个体化模板。然后通过快速原型(RP)技术制作同时包含针道和面部特征信息的个体化模板。所有患者均在个体化模板和 CT 的引导下接受(125)I 种子间质植入。个体化模板定位容易且准确,并且稳定。植入后,通过 CT 和 TPS 进行治疗质量评估。种子和剂量分布(D(90)、V(100)、V(150))符合治疗要求。临床实践证实,这种方法可以使植入更简单、更准确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76ad/3483848/593203825e11/rrs04601.jpg

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