School of Nursing, Nantong University, Nantong, Jiangsu, People's Republic of China.
J Wound Ostomy Continence Nurs. 2012 Sep-Oct;39(5):495-9. doi: 10.1097/WON.0b013e318265222a.
The purpose of this study was to determine whether diabetes mellitus is associated with increased likelihood of surgery-related (perioperative) pressure ulcers.
The MEDLINE and Thomson Reuters Web of Knowledge electronic databases were searched for studies of diabetes as a risk factor for surgery-related pressure ulcers in case-control or cohort design; studies were limited to those published in English. Data from studies meeting inclusion criteria were pooled, and a meta-analysis was completed using the meta-analysis of observational studies in epidemiology (MOOSE) guidelines. Odds ratios for surgery-related pressure ulcers were calculated for patients with and without diabetes mellitus.
Six observational studies were identified involving a total of 2453 patients. When compared to patients with normal glucose tolerance, persons with diabetes mellitus were more likely to experience surgery-related pressure ulcers (odds ratio = 2.15; 95% confidence interval: 1.62-2.84).
Our meta-analysis indicates that patients with diabetes mellitus are slightly more than twice as likely to develop surgery-related pressure ulcers as compared to patients with normal glucose tolerance.
本研究旨在确定糖尿病是否与手术相关（围手术期）压疮的发生几率增加有关。
通过 MEDLINE 和 Thomson Reuters Web of Knowledge 电子数据库，检索了以糖尿病为手术相关压疮风险因素的病例对照或队列设计研究；研究仅限于英文发表的研究。对符合纳入标准的研究数据进行汇总，并使用观察性研究的荟萃分析流行病学（MOOSE）指南完成荟萃分析。计算了有和没有糖尿病的患者发生手术相关压疮的比值比。
共确定了 6 项观察性研究，共涉及 2453 名患者。与血糖正常的患者相比，患有糖尿病的患者更有可能发生手术相关压疮（比值比=2.15；95%置信区间：1.62-2.84）。
我们的荟萃分析表明，与血糖正常的患者相比，糖尿病患者发生手术相关压疮的几率略高于两倍。
