Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Education and Research Hospital, Devlet Mah Subay Loj. No: 19/11 Yenisehir, Ankara, Turkey.
Arch Gynecol Obstet. 2012 Dec;286(6):1597-600. doi: 10.1007/s00404-012-2488-y. Epub 2012 Aug 4.
To analyze the changes in the endometrial thickness in infertile polycystic ovary syndrome (PCOS) patients throughout an entire menstrual cycle and compare the changes to those seen in infertile patients without PCOS.
This prospective, cross-sectional study was conducted in a total of 58 non-obese, infertile women with PCOS. The endometrial thickness was measured at three different times throughout the menstrual cycle by ultrasound. Age- and body mass index (BMI)-matched control group consisted of 62 non-obese infertile patients without PCOS. Demographic, hormonal and the ultrasonographic measurements of the two groups were compared.
Day 3 levels of LH were significantly different between the groups (p=0.013). Ovarian volume measurement was significant between the groups (p=0001). All the endometrial thickness measurements in the early, mid-cycle and late luteal phases were also significantly different; p=0.001 for all.
The study demonstrated an increased endometrial stripe measurements throughout a menstrual cycle in infertile patients with PCOS, when compared to infertile patients without PCOS.
分析整个月经周期中不孕多囊卵巢综合征（PCOS）患者的子宫内膜厚度变化，并将其与不孕但非 PCOS 患者的变化进行比较。
本前瞻性、横断面研究共纳入 58 名非肥胖不孕 PCOS 患者。通过超声在月经周期的三个不同时间点测量子宫内膜厚度。年龄和体重指数（BMI）匹配的对照组由 62 名非肥胖不孕但非 PCOS 患者组成。比较两组的人口统计学、激素和超声测量值。
两组间第 3 天的 LH 水平差异有统计学意义（p=0.013）。卵巢体积测量值两组间差异有统计学意义（p=0.0001）。在早期、中期和黄体晚期的所有子宫内膜厚度测量值也均有显著差异，p 值均为 0.001。
与不孕但非 PCOS 患者相比，本研究显示不孕 PCOS 患者在整个月经周期中子宫内膜带的测量值增加。
