Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India.
Hong Kong Med J. 2012 Aug;18(4):346-7.
We report the case of a 35-year-old man from North India who presented with generalised tonic-clonic seizures and was found to have ring-enhancing brain lesions. He had a coincident adrenal mass lesion. Cultures from both regions grew Histoplasma capsulatum. He improved on treatment with itraconazole. This case is being reported since cerebral ring-enhancing lesions are rarely associated with histoplasmosis, and coincident adrenal involvement is also a rarity in an immunocompetent individual.
我们报告了一例来自印度北部的 35 岁男性患者,他出现全身强直阵挛性发作,并被发现有环形增强的脑部病变。他还有一个同时存在的肾上腺肿块病变。来自这两个区域的培养物都生长出荚膜组织胞浆菌。他接受伊曲康唑治疗后病情有所改善。本病例被报道是因为脑环形增强病变很少与组织胞浆菌病有关,而在免疫功能正常的个体中同时发生肾上腺受累也很少见。