de Jong Marrigje, Perez Ronen, Adelman Cahtia, Chordekar Shai, Rubin Melissa, Kriksunov Leonid, Sohmer Haim
Department of Medical Neurobiology, Institute of Medical Research, Israel.
J Basic Clin Physiol Pharmacol. 2011 Aug 26;22(3):55-8. doi: 10.1515/jbcpp.2011.014.
A new mode of auditory stimulation has been demonstrated which is through soft tissue conduction (STC). It involves evoking auditory sensations by applying the clinical bone vibrator to the skin over soft tissue (not over bone) sites on the head and neck.
This study was designed to show that stimulation by STC excites the cochlea in a way similar to that of air conduction (AC) and bone conduction (BC).
It is shown here that auditory nerve brainstem evoked response (ABR) thresholds in mice and in the fat sand rat to AC, to BC and to STC stimulation are all elevated following administration of drugs (salicylic acid and furosemide) which depress the cochlear amplifier. In addition, the present study brings evidence that STC stimulation is not a variant of BC since the sound pressures recorded in the occluded external auditory canal (the occlusion effect) in response to STC are significantly smaller than that to BC stimulation, though both are of equal loudness.
This new mode, STC, therefore appears to bypass the middle ear mechanisms and consequently may contribute to auditory diagnosis.
一种新的听觉刺激模式已得到证实，即通过软组织传导（STC）。它包括将临床骨振动器应用于头颈部软组织（而非骨骼）部位的皮肤上来诱发听觉感受。
本研究旨在表明，STC刺激以类似于气导（AC）和骨导（BC）的方式刺激耳蜗。
此处表明，在给予抑制耳蜗放大器的药物（水杨酸和速尿）后，小鼠和肥尾沙鼠对AC、BC和STC刺激的听神经脑干诱发电位（ABR）阈值均升高。此外，本研究提供了证据表明STC刺激不是BC的变体，因为尽管对STC和BC刺激的响度相同，但对STC刺激在闭塞外耳道中记录的声压明显小于对BC刺激记录的声压。
因此，这种新的模式STC似乎绕过了中耳机制，从而可能有助于听觉诊断。
