Schwarz S, Wegener H, Blobel H
Institut für Bakteriologie und Immunologie, Justus Liebig Universität Giessen, FRG.
J Appl Bacteriol. 1990 Dec;69(6):845-9. doi: 10.1111/j.1365-2672.1990.tb01582.x.
A small plasmid of 2.35 kb, isolated from a porcine Staphylococcus hyicus-culture, was found to be responsible for constitutive resistance to macrolide/lincosamide antibiotics. This plasmid-encoded property could be established by interspecific transformation experiments. The plasmid from porcine Staph. hyicus was designated as pSE2. It differed on the basis of its restriction map from the macrolid/lincosamid resistance (MLR-)-plasmids of other staphylococcal species from infections of humans. Furthermore, the pSE2 plasmid encoded two proteins of approximately 20.5 and 30 kDa.
从猪源猪葡萄球菌培养物中分离出一个2.35 kb的小质粒，发现它对大环内酯类/林可酰胺类抗生素具有组成性抗性。这种质粒编码的特性可通过种间转化实验得以证实。来自猪源猪葡萄球菌的质粒被命名为pSE2。根据其限制性图谱，它与来自人类感染的其他葡萄球菌种的大环内酯/林可酰胺抗性（MLR-）质粒不同。此外，pSE2质粒编码两种分子量约为20.5 kDa和30 kDa的蛋白质。
