Institute of Animal Physiology and Genetics CAS, v.v.i., Brno, Czech Republic.
Int J Oral Maxillofac Surg. 2013 Mar;42(3):369-75. doi: 10.1016/j.ijom.2012.07.001. Epub 2012 Aug 4.
Many different surgical and non-surgical techniques are used for the treatment of temporomandibular joint (TMJ) hypermobility. One of these methods is autologous blood injection into the TMJ. The fate of the autologous blood used for treatment of recurring condylar dislocation is still not completely understood. The authors used 12 pigs (Sus scrota f. domestica) as a model species for autologous blood delivery into the TMJ. Blood injection was followed by histopathological analysis at different times after treatment (1h, 1, 2 and 4 weeks). Samples were examined by magnetic resonance imaging, macroscopic and histological methods. The deposition of the remaining blood was observed in the form of clots in the distal parts of the upper joint cavity 1h and 1 week after treatment. 2 weeks after treatment, small blood clots were still apparent in the distal part of the upper joint cavity. 4 weeks after surgery, no remnants of blood, changes or adhesions were apparent inside the TMJ. No morphological or histological changes were observed in the TMJ after the injection of autologous blood suggesting another mechanism is involved in the hypermobility treatment.
许多不同的手术和非手术技术被用于治疗颞下颌关节（TMJ）过度活动。其中一种方法是将自体血液注入 TMJ。用于治疗复发性髁突脱位的自体血液的命运仍不完全清楚。作者使用 12 头猪（Sus scrota f. domestica）作为将自体血液输送到 TMJ 的模型物种。在治疗后不同时间（1h、1、2 和 4 周）进行血液注射后进行组织病理学分析。通过磁共振成像、宏观和组织学方法检查样本。在治疗后 1h 和 1 周，在关节上腔的远端部分以凝块的形式观察到剩余血液的沉积。治疗后 2 周，在上关节腔的远端仍可见少量血凝块。手术后 4 周，TMJ 内无血液残留、变化或粘连。自体血液注射后 TMJ 未观察到形态或组织学变化，提示另一种机制参与了过度活动的治疗。
