Varedi Payam, Bohluli Behnam
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran,
Oral Maxillofac Surg. 2015 Sep;19(3):243-52. doi: 10.1007/s10006-015-0500-y. Epub 2015 May 3.
The purpose of this article is to review the English literature about the efficacy and safety of autologous blood injection in treating patients suffering from chronic recurrent temporomandibular joint dislocation. In this article, we highlight the key trials and recent directions about this modality and discuss about the mechanism, advantages, and disadvantages of this approach.
A literature search was performed using PubMed, Medline, and Ovid Medline databases to identify articles reporting on the injection of autologous blood for treatment of chronic recurrent dislocation of temporomandibular joint. Other references cited in the retrieved reports, as well as the "related articles" tool in PubMed Medline, were also checked to improve the search and, if relevant, were included in the study. The search was restricted to articles published in the English language.
Seven studies meeting the inclusion criteria were reviewed. The selected articles included four prospective clinical trials and three case report articles.
There are a few articles about the clinical use of autologous blood for treating patients with chronic recurrent temporomandibular joint dislocation. Reviewing of the literature shows that there are successful results about this modality, but there are still some concerns about it in terms of the effect of the injected blood on the articular cartilage and formation of fibrous or bony ankylosis.
本文旨在综述英文文献中关于自体血注射治疗慢性复发性颞下颌关节脱位患者的疗效和安全性。在本文中，我们重点介绍了关于这种治疗方式的关键试验和最新研究方向，并讨论了该方法的机制、优缺点。
使用PubMed、Medline和Ovid Medline数据库进行文献检索，以确定报道自体血注射治疗颞下颌关节慢性复发性脱位的文章。还检查了检索报告中引用的其他参考文献以及PubMed Medline中的“相关文章”工具，以完善检索，如有相关内容则纳入研究。检索仅限于以英文发表的文章。
对七项符合纳入标准的研究进行了综述。所选文章包括四项前瞻性临床试验和三篇病例报告文章。
关于自体血在治疗慢性复发性颞下颌关节脱位患者中的临床应用的文章较少。文献综述表明，这种治疗方式有成功的结果，但在注入的血液对关节软骨的影响以及纤维性或骨性强直的形成方面仍存在一些问题。
