Machon Vladimir, Levorova Jitka, Hirjak Dusan, Wisniewski Marcin, Drahos Milan, Sidebottom Andrew, Foltan Rene
Department of Oral and Maxillofacial Surgery, General University Hospital, U Nemocnice 2, 120 00, Prague, Czech Republic.
Department of Oral and Maxillofacial Surgery, Faculty Hospital Bratislava-Ruzinov, Bratislava, Slovakia.
Oral Maxillofac Surg. 2018 Mar;22(1):53-57. doi: 10.1007/s10006-017-0666-6. Epub 2017 Nov 30.
The objective of the study was to compare results of treatment for chronic recurrent temporomandibular joint dislocation (CRTMD) by autologous blood injection (ABI) using two different methods of administration (combination intra- and peri-articular, and peri-articular alone).
Forty patients diagnosed with CRTMD were randomly divided into two groups of 20 each (A and B). Group A were treated by intra- and peri-articular blood injection, group B were treated by peri-articular injection alone. The follow-up was done at 1, 3, 6, and 12 months. The study assessed presence of dislocations, pain (VAS, 0-10), interincisal mouth opening (IMO), and the presence of sound phenomena. The treatment was considered successful in patients without the persistence of CRTMD symptoms, as well as with a VAS of 0-1.
After 12 months, a beneficial therapeutic effect in group B was seen in 11 patients, while 16 patients from group A had a therapeutic effect.
Intra- and peri-articular ABI is more effective than peri-articular blood application alone in the treatment of CRTMD, although the difference was not statistically significant.
本研究的目的是比较采用两种不同给药方法（关节内和关节周围联合注射以及单纯关节周围注射）的自体血注射（ABI）治疗慢性复发性颞下颌关节脱位（CRTMD）的效果。
40例被诊断为CRTMD的患者被随机分为两组，每组20例（A组和B组）。A组采用关节内和关节周围注射血液治疗，B组仅采用关节周围注射治疗。在1、3、6和12个月时进行随访。该研究评估脱位的存在情况、疼痛（视觉模拟评分法，0 - 10分）、切牙间开口度（IMO）以及声音现象的存在情况。对于没有CRTMD症状持续存在且视觉模拟评分为0 - 1分的患者，治疗被认为是成功的。
12个月后，B组有11例患者出现有益的治疗效果，而A组有16例患者有治疗效果。
在CRTMD的治疗中，关节内和关节周围自体血注射比单纯关节周围注射血液更有效，尽管差异无统计学意义。
