Pain Research Group, Federal University of Maranhão, São Luís, Brazil.
J Pain Symptom Manage. 2012 Aug;44(2):239-51. doi: 10.1016/j.jpainsymman.2011.08.014.
Chronic pain (CP) with and without neuropathic characteristics is a public health problem. This is the first population-based study in South America, and the third in the world, to use the Douleur Neuropathique 4 Questions (DN4) tool in epidemiologic studies.
The objectives were to estimate the prevalence and associated factors of CP with and without neuropathic characteristics in São Luís, Brazil.
We surveyed 1597 people. The DN4 questionnaire was applied. Poisson regression was used to analyze the risk factors.
The prevalence of CP was 42%, and 10% had CP with neuropathic characteristics (CPNC). The results showed that female sex and age ≥30 years were associated with an increased prevalence of CP (P<0.001) and education ≥12 years with a reduction in the prevalence of CP. The sensations listed in the DN4 were more common in people with CPNC and most frequent were pins and needles (87.9%). The cephalic region (36%) and limbs (51%) were the locations most affected. Most respondents felt pain between six months and four years (51.6%), with daily frequency (45%). Pain intensity, the impediments caused by pain, and sadness were more prevalent in people who had CPNC (P<0.001). Health status was regular for most, 50.9% did not know the cause of their pain, 64.1% used drugs, and only 7% had consulted with a pain specialist. Dissatisfaction with treatment was reported by 55%.
CP with and without neuropathic characteristics is a public health problem in Brazil, with high prevalence and great influence on people's daily lives.
伴有或不伴有神经病理性特征的慢性疼痛（CP）是一个公共卫生问题。这是南美洲首例也是世界范围内第三例在流行病学研究中使用神经病理性疼痛 4 问问卷（DN4）工具的研究。
本研究旨在评估巴西圣路易斯市伴有和不伴有神经病理性特征的 CP 的流行情况及其相关因素。
我们调查了 1597 人。应用 DN4 问卷。采用 Poisson 回归分析风险因素。
CP 的患病率为 42%，10%的 CP 伴有神经病理性特征（CPNC）。结果表明，女性和年龄≥30 岁与 CP 患病率增加相关（P<0.001），而教育程度≥12 年与 CP 患病率降低相关。DN4 列出的感觉在 CPNC 患者中更为常见，最常见的是刺痛感（87.9%）。头痛（36%）和四肢（51%）是最常受影响的部位。大多数受访者的疼痛持续时间为 6 个月至 4 年（51.6%），每天发作（45%）。CPNC 患者的疼痛强度、疼痛引起的障碍和悲伤更为常见（P<0.001）。大多数人的健康状况良好，50.9%的人不知道疼痛的原因，64.1%的人使用药物，只有 7%的人咨询过疼痛专家。55%的人对治疗不满意。
CP 伴有和不伴有神经病理性特征是巴西的一个公共卫生问题，其患病率较高，对人们的日常生活有很大影响。
