Adoukonou T, Gnonlonfoun D, Kpozehouen A, Adjien C, Tchaou B, Tognon-Tchegnonsi F, Adechina H, Covi R, Houinato D
Unité d'enseignement et de recherche de neurologie, faculté de médecine université de Parakou, Parakou, Bénin; Unité de neurologie du service de médecine, hôpital de Parakou, Parakou, Bénin.
Unité d'enseignement et de recherche de neurologie, faculté des sciences de la santé de l'université d'Abomey-Calavi, Cotonou, Bénin.
Rev Neurol (Paris). 2014 Nov;170(11):703-11. doi: 10.1016/j.neurol.2014.07.013. Epub 2014 Oct 22.
The burden of chronic and neuropathic pain is high making it an important public health problem. The epidemiology is not well known in the general population in sub-Saharan Africa. We aimed to determine the prevalence of chronic pain with a neuropathic component at Tititou in Parakou in northeastern Benin. A cross-sectional study was conducted from 1st April to 31 May 2012 and included 2314 people in a door-to-door survey. Chronic pain was defined as pain occurring for more than three months. Neuropathic pain was assessed with the DN4 score. A neurological exam was performed by a young physician for all people with chronic pain. During the interview, sociodemographic data, past medical history, weight and height were recorded. Multivariate logistic regression was performed to analyze the main associated factors. Among the 2314 people included in this survey, 49.7% were male. The mean age was 32.3 ± 13.1 years. Nine hundred seven reported pain occurring for more than 3 months. The prevalence of chronic pain was 39.2% (CI95%: 29.3-34.7). It was more frequent in females, older people, among diabetics, people with a history of any surgery, stroke, brain trauma, and alcoholism. The prevalence of chronic pain with a neuropathic component was 6.3% (CI95%: 5.0-7.9). The main associated factors were age, matrimonial status, professional occupation, body mass index, diabetes, history of zoster, history of any surgery, brain trauma. People with neuropathic pain often reported pain with burning (87.6%), prickling (82.8%), numbness (66.9%), tingling (63.4%), and lightning pain (48.3%). The main locations were the lower limbs and low back pain. This study suggested the high frequency of chronic neuropathic pain in the general population in Parakou compared with rates reported in western countries.
慢性和神经性疼痛负担沉重,使其成为一个重要的公共卫生问题。在撒哈拉以南非洲的普通人群中,其流行病学情况尚不为人所知。我们旨在确定贝宁东北部帕拉库蒂蒂图慢性疼痛伴神经性成分的患病率。于2012年4月1日至5月31日进行了一项横断面研究,通过挨家挨户调查纳入了2314人。慢性疼痛定义为持续超过三个月的疼痛。使用DN4评分评估神经性疼痛。由一名年轻医生对所有慢性疼痛患者进行神经系统检查。在访谈过程中,记录了社会人口统计学数据、既往病史、体重和身高。进行多变量逻辑回归分析主要相关因素。在本次调查纳入的2314人中,49.7%为男性。平均年龄为32.3±13.1岁。907人报告疼痛持续超过3个月。慢性疼痛患病率为39.2%(95%置信区间:29.3 - 34.7)。在女性、老年人、糖尿病患者、有任何手术史、中风、脑外伤和酗酒史的人群中更为常见。慢性疼痛伴神经性成分的患病率为6.3%(95%置信区间:5.0 - 7.9)。主要相关因素为年龄、婚姻状况、职业、体重指数、糖尿病、带状疱疹病史、任何手术史、脑外伤。神经性疼痛患者常报告有灼痛(87.6%)、刺痛(82.8%)、麻木(66.9%)、刺痛感(63.4%)和闪电样疼痛(48.3%)。主要部位是下肢和下背部疼痛。这项研究表明帕拉库普通人群中慢性神经性疼痛的发生率高于西方国家报告的发生率。