Das G D
Department of Biological Sciences, Lilly Hall of Life Sciences, Purdue University, West Lafayette, IN 47907.
Neurosci Biobehav Rev. 1990 Winter;14(4):389-401. doi: 10.1016/s0149-7634(05)80061-2.
Literature on transplantation of neural and nonneural tissues into the brains of host animals is reviewed in the perspective of various issues. The two dominant issues determining this research were elucidation of embryological processes underlying the development of the nervous system and regeneration in the host brain. A comprehensive review of studies on regeneration in the central nervous system (CNS), using this technique of transplantation, indicates that regeneration of axonal fibers is small in magnitude and extent, and that it is more directly related to the trauma caused to the brain than to any other variable. This literature review attempts to provide a perspective to the contemporary research on neural transplantation and on regeneration in the CNS.
本文从多个角度对有关将神经组织和非神经组织移植到宿主动物大脑的文献进行了综述。决定这项研究的两个主要问题是阐明神经系统发育背后的胚胎学过程以及宿主大脑中的再生情况。对利用这种移植技术进行的中枢神经系统（CNS）再生研究的全面综述表明，轴突纤维的再生在数量和范围上都很小，而且它与大脑受到的创伤的关系比与任何其他变量的关系更为直接。这篇文献综述试图为当代神经移植和中枢神经系统再生研究提供一个视角。
