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肝细胞癌经动脉治疗的新进展有哪些?

What's New in Transarterial Therapies for Hepatocellular Carcinoma?

作者信息

May Benjamin J, Murthy Ravi, Madoff David C

出版信息

Gastrointest Cancer Res. 2012 May;5(3 Suppl 1):S14-9.

Abstract

Transarterial therapies play an important role in the treatment of hepatocellular carcinoma, both in a palliative setting and as an adjunct to surgery. These therapies exploit the dual blood supply of the liver to selectively target tumors via the hepatic artery, while sparing nontumorous liver. Currently available therapies include transarterial embolization; chemoembolization, with or without drug-eluting beads; and radioembolization. Transarterial techniques are also being used in the development of novel therapies. This article provides an outline of the technical and clinical applications of intraarterial therapies in the treatment of HCC and highlights pertinent future directions.

摘要

经动脉治疗在肝细胞癌的治疗中发挥着重要作用,无论是在姑息治疗还是作为手术辅助治疗方面。这些治疗方法利用肝脏的双重血液供应,通过肝动脉选择性地靶向肿瘤,同时保护非肿瘤性肝脏。目前可用的治疗方法包括经动脉栓塞术;化疗栓塞术,使用或不使用载药微球;以及放射性栓塞术。经动脉技术也正被用于新型治疗方法的研发。本文概述了动脉内治疗在肝癌治疗中的技术和临床应用,并突出了相关的未来发展方向。

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